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Animal Models, by Disease/Condition |
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Abbreviations |
AFIP=
Armed Forced Institute of Pathology, Washington, DC |
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DRM Wkshop= DRM Wkshop
Demands for Rhesus Monkeys in Biomedical Research: A Workshop Report:
Institute for Laboratory Animal Research(ILAR) 500 5th ST. NW , Washington,
DC 20001 Tel 202 334 2590 NO Journal Reference |
|
| R |
Disease/Condition |
Area |
Animal |
Abstracts and References |
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Notes |
Notes |
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| A |
ß-Mannosidosis |
|
goats |
18th Fascicle, AFIP, 1991 |
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| H |
abnormal adherence junctions in fetal heart; reduced
angiogenesis in fetus and placenta |
Heart |
mice |
Reference
11566879 |
collagen type XIII, mutation |
transgenic overexpression |
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| H |
abnormal cardiac structure and function |
Heart |
mice |
Reference
10409661'); |
myosin light chain 2, cardiac regulatory |
transgenic |
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| H |
abnormal lung development |
Lung |
mice |
Reference
11784039'); |
PDGF-A |
transgenic |
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| H |
abnormal yolk sac vasculogenesis, embryonic death |
Heart |
mice |
Reference
10827131'); |
transforming growth factor (TGF)-beta(1) |
transgenic cardiovascular overexpression |
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| LM |
acanthamoeba |
|
monkey |
Reference 1165552 |
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| A |
Accelerated Lupus
Nephritis |
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mice. |
18th Fascicle, AFIP, 1991 |
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| H |
acid-induced lung injury/ARDS |
Lung |
mice |
Reference
10525045'); |
platelet-activating factor receptor (PAFR) |
transgenic and knockout |
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| A |
Acquired Immune
Deficiency Syndrome |
|
monkeys |
13th Fascicle, AFIP, 1984 |
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| A |
Acquired
Immunodeficienct Syndrome |
|
rabbits |
14th Fascicle, AFIP, 1985 |
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| A |
Acquited
Immunodefiency Syndrome |
|
cats. |
16th Fascicle, AFIP, 1987 |
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| A |
Acrodermatitis
Enteropathica |
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cattle |
7th Fascicle, AFIP, 1978 |
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| A |
Acromegaly |
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dogs |
14th Fascicle, AFIP, 1985 |
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| A |
Active Chronic Hepatitis |
|
mice |
5th Fascicle, AFIP, 1976 |
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| A |
Acute Acalculous
Cholectstitis |
|
rabbits |
16th Fascicle, AFIP, 1987 |
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| A |
Acute Bacterial Otitis
Media |
|
cat |
19th Fascicle, AFIP, 1993 |
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| A |
Acute B-Lymphoblastic
Leukemia |
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EF-myc transgenic rabbit |
19th Fascicle, AFIP, 1993 |
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| H |
acute glomerulonephritis |
Blood |
mice |
Reference
9382884'); |
Mac-1 |
knockout |
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| H |
acute lung injury |
Lung |
mice |
Reference
10564191'); |
transforming growth factor-alpha(TGF-alpha) |
transgenic |
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| H |
acute lung injury; pulmonary inflammation |
Lung |
mice |
Reference
10194479'); |
SOD3 (EC-SOD) |
transgenic |
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| A |
Acute Lymphoblastic
Leukemia |
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guinea pigs. |
8th Fascicle, AFIP, 1979 |
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| A |
Acute Respiratory
Distress Syndrome |
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rabbits |
12th Fascicle, AFIP, 1983 |
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| H |
acute respiratory distress syndrome (ARDS) |
Lung |
mice |
Reference
10535991'); |
Nrf2 |
knockout |
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| A |
Acute Toxoplasmosis |
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woolly monkey |
1st Fascicle, AFIP, 1972: |
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| A |
Acute Viral
Gastroenteritis |
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dogs |
8th Fascicle, AFIP, 1979 |
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| A |
Adenocarcimona of Rete
Testis |
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mice |
16th Fascicle, AFIP, 1987 |
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| LM |
adenocarcinoma |
|
monkey, marmoset |
Reference 417316 |
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| A |
Adenocarcinoma of the
Colon |
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rat |
3rd Fascicle, AFIP, 1974: |
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| A |
Adenocarcinoma of the
Prostate |
|
rats |
7th Fascicle, AFIP, 1978 |
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| A |
Adenosis
and Clear-Cell Carcinoma of the Vagina and Cervis |
|
mice |
6th Fascicle, AFIP, 1977 |
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| LM |
Adenoviridae Infections |
|
monkey, macaca |
Reference 4360741 |
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| D |
Adrenal dysfunction |
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Monkey, Marmosets |
DRM Wkshop |
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| A |
Adrenal Necrosis |
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hamsters |
7th Fascicle, AFIP, 1978 |
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| A |
Adult Respiratory
Disterss Syndrome |
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pigs |
17th Fascicle, AFIP, 1989 |
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| A |
Adult Respiratory
Distress Syndrome |
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monkeys |
16th Fascicle, AFIP, 1987 |
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| D |
Aging |
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Baboons |
DRM Wkshop |
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| D |
Aging |
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Monkey, Marmosets |
DRM Wkshop |
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| D |
Aging |
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Monkey, Owl Monkey |
DRM Wkshop |
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| D |
Aging |
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Monkey, Squirrel Monkeys |
DRM Wkshop |
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| LM |
Aging |
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monkeys |
Reference 1688300 |
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| LM |
AIDS |
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chimpanzee |
Reference 2517468 |
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| LM |
AIDS |
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chimpanzee |
Reference 3878410 |
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| LM |
AIDS |
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gibbon |
Reference 2517468 |
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| H |
AIDS |
Blood |
mice |
Reference
9565636 |
CD4 and CXCR4 |
transgenic |
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| H |
AIDS |
Blood |
mice |
Reference
7494270'); |
HIV Tat |
transgenic |
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| LM |
AIDS |
|
mice |
Reference 2517468 |
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| LM |
AIDS |
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monkey |
Reference 1645558 |
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| LM |
AIDS |
|
monkey |
Reference 6133120 |
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| LM |
AIDS |
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monkey , rheuses macaques |
Reference 9765427 |
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| D |
AIDS |
|
Monkey, African Green Monkey |
DRM Wkshop |
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| LM |
AIDS |
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monkey, fascicularis |
Reference 6136748 |
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| LM |
AIDS |
|
monkey, macaca |
Reference 6827746 |
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| LM |
AIDS |
|
monkey, macaca |
Reference 6130381 |
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| LM |
AIDS |
|
monkey, macaca mulatta |
Reference 1970381 |
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| LM |
AIDS |
|
monkey, macaca mulatta |
Reference 9394615 |
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| LM |
AIDS |
|
monkey, macaca mulatta |
Reference 3037910 |
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| LM |
AIDS |
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monkey, macaca mulatta |
Reference 3529592 |
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| LM |
AIDS |
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monkey, macaca mulatta |
Reference 3461210 |
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| LM |
AIDS |
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monkey, macaca mulatta |
Reference 2984090 |
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| LM |
AIDS |
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monkey, macaca mulatta |
Reference 6610800 |
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| LM |
AIDS |
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monkey, macaca mulatta |
Reference 6232704 |
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| LM |
AIDS |
|
monkey, macaca mulatta |
Reference 6200929 |
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| D |
AIDS |
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Monkey, Pigtailed Macaques |
DRM Wkshop |
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| LM |
AIDS |
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monkey, rheuses |
Reference 2517468 |
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| LM |
AIDS |
|
monkey, rheuses macaque |
Reference 2547966 |
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| LM |
AIDS |
|
monkey, rheuses macaque |
Reference 2547959 |
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| LM |
AIDS |
|
rabbits |
Reference 2517468 |
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| LM |
AIDS -neg finding |
|
baboons |
Reference 2547959 |
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| H |
airway epithelial ion transport |
Lung |
mice |
Reference
10473606'); |
P2Y(2)-receptor |
knockout |
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| H |
airway hyperreactivity/emphysema |
Lung |
mice |
Reference
10843940'); |
interleukin-6 (IL-6) and interleukin-11 (IL-11) |
transgenic |
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| H |
airway inflammation |
Lung |
mice |
Reference
9476901'); |
Nerve Growth Factor (NGF) |
transgenic |
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| H |
airway inflammation and fibrotic responses |
Lung |
mice |
Reference
8981933'); |
interleukin-11 (IL-11) |
transgenic |
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| H |
airway inflammation and injury |
Lung |
mice |
Reference
9490661'); |
interleukin-1 receptor antagonist (IL-1ra) (Human) |
transgenic |
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| H |
airways hyperreactivity;asthma |
Lung |
mice |
Reference
10657668'); |
interleukin-5(IL-5) |
transgenic |
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| H |
alcohol cardiomyopathy |
Heart |
mice |
Reference
10525098 |
alcohol dehydrogenase |
transgenic overexpression |
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| A |
Alcoholic Fatty Livers |
|
rats. |
2nd Fascicle, AFIP, 1973: |
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| D |
Alcoholic liver disease |
|
Baboons |
DRM Wkshop |
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| LM |
alcoholic liver disease |
|
baboons |
Reference 1237225 |
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| LM |
alcoholic liver disease |
|
rats |
Reference 1237225 |
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| A |
Alimentary Toxic Aleukia |
|
cats. |
10th Fascicle, AFIP, 1981 |
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| H |
allergen induced airway inflammation |
Lung |
mice |
Reference
9091582'); |
interleukin-10 (IL-10) |
knockout |
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| H |
allergen induced airway inflammation |
Lung |
mice |
Reference
9565645'); |
STAT-6 |
knockout |
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| H |
allergic airway inflammation |
Lung |
mice |
Reference
9351584'); |
interleukin-4 (IL-4) |
knockout |
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| H |
allergic airways disease / asthma |
Lung |
mice |
Reference
9886418'); |
NOS2 (iNOS) |
knockout |
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| H |
allergic asthma |
Lung |
mice |
Reference
11830666 |
CCR3 |
knockout |
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| H |
allergic asthma |
Lung |
mice |
Reference
11466391 |
eosinophil peroxidase |
knockout |
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| H |
allergic asthma |
Lung |
mice |
Reference
11591792'); |
HLA-DQ/Human CD4 |
double transgenic-double knockout |
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| H |
allergic inflammation |
Blood |
mice |
Reference
9146893'); |
interleukin-5 (IL-5) |
transgenic |
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| A |
Alpha1-Antitrypsin
Deficiency |
|
turkeys |
6th Fascicle, AFIP, 1977 |
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| H |
alpha-thalassemia |
Blood |
mice |
Reference
7550311 |
hemoglobin, alpha chain |
knockout |
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| H |
alpha-thalassemia, hemoglobin H disease |
Blood |
mice |
Reference
8781443 |
hemoglobin, alpha chain |
knockout and other |
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| H |
alveolar fluid clearance |
Lung |
mice |
Reference
11557593 |
beta-2-adrenergic receptor |
transgenic overexpression |
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| H |
alveolar morphogenesis; alveolarization |
Lung |
mice |
Reference
10919981'); |
retinoic acid receptor-gamma (RARgamma) |
knockout |
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| H |
alveolar proteinosis |
Lung |
mice |
Reference
8609219 |
GM-CSF |
(bi)transgenic |
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| H |
alveolar proteinosis |
Lung |
mice |
Reference
7697542'); |
interleukin-3 (IL-3) receptor, beta c subunit; GM-CSF receptor, beta c subunit; interleukin-5 (IL-5) |
knockout |
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| H |
alveolitis |
Lung |
mice |
Reference
8630558 |
C-reactive protein (CRP) |
transgenic |
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| LM |
Alzheimer's |
|
monkeys |
Reference 1688300 |
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| LM |
Amblyopia |
|
monkey, macaca nemestrina |
Reference 7461928 |
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| LM |
amebae infections |
|
monkey |
Reference 1165552 |
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| A |
Amebic Dysentery |
|
guinea pigs |
8th Fascicle, AFIP, 1979 |
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| M |
amelogenesis imperfecta |
|
mice |
Amelx |
B6;129-Amelxtm1Kul/Unc |
Targeted Mutation / Knockout |
MMRRC:0044-UNC |
MMRRC Catalog |
Live Colony |
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| MM |
amelogenesis imperfecta |
|
mice |
Amelx |
Amelx |
Targeted Mutation / Knockout |
MMRRC:0044-UNC |
MMRRC Catalog |
B6;129-Amelxtm1Kul/Unc |
Live Colony |
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| LM |
Amyloid neuropathies |
|
monkeys |
Reference 1688300 |
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| LM |
amyloidosis |
|
monkey |
Reference 6395673 |
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| A |
Amyloidosis |
|
ducks |
8th Fascicle, AFIP, 1979 |
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| A |
Amyloidosis,
Spontaneous and Induced |
|
mice |
2nd Fascicle, AFIP, 1973: |
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| A |
Analbuminemia |
|
rat |
20th Fascicle, AFIP, 1995 |
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| LM |
Anemia, due to B19 parovirus |
|
monkeys, cynomolgus macaques |
Reference 8163659 |
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| H |
angioedema |
Heart |
mice |
Reference
11956243 |
C1 inhibitor (C1INH) |
disruption by gene trapping |
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| A |
Angioimmunoblastic
Lymphadenopathy |
|
hamsters |
8th Fascicle, AFIP, 1979 |
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| A |
Angioimmunoblastic
Lymphadenopathy With Dysproteinemia |
|
mice |
9th Fascicle, AFIP, 1980 |
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| A |
Anti-GBM Antibody |
|
horses |
8th Fascicle, AFIP, 1979 |
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| A |
Anti-Glomeruler-Basement-Membrane
Glomerulonephritis |
|
sheep |
9th Fascicle, AFIP, 1980 |
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| A |
Anti-Tubular-Basement-Membrane-Antibody
Tubulointerstitial Nephritis |
|
guinea pigs |
9th Fascicle, AFIP, 1980 |
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| LM |
Aortic Diseases |
|
monkey, macaca mulatta |
Reference 1123845 |
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| H |
aplastic anemia |
Blood |
mice |
Reference
9607930'); |
perforin and T cell receptor and tumor necrosis factor receptor type 1 |
knockout, transgenic, and other |
|
|
|
|
|
|
|
| H |
arrhythmia |
Heart |
mice |
Reference
12077327'); |
Nhlh1 |
knockout |
|
|
|
|
|
|
|
| LM |
Arteriosclerosis |
|
monkey, macaca mulatta |
Reference 6605917 |
|
|
|
|
|
|
|
|
|
| LM |
Arteriosclerosis |
|
monkey, macaca mulatta |
Reference 1123845 |
|
|
|
|
|
|
|
|
|
| LM |
Artherosclerosis |
|
Monkey |
Reference \10090078 |
|
|
|
|
|
|
|
|
|
| RR |
arthritis inflammatory bowel disease |
|
rat |
Reference |
HLA B27 |
|
LEW-Tg(HLA-B*2705m1,B2M)133-1Trg |
CM: Rat Resource Center |
RRRC:0043 |
Transgenic |
Live Colony |
|
|
| LM |
arthritis, degenerative |
|
monkey, rheuses macaque |
Reference 2780974 |
|
|
|
|
|
|
|
|
|
| LM |
Arthritis, inflammatory |
|
monkey, Cayo Santiago rhuesus
macaques |
Reference 9093772 |
|
|
|
|
|
|
|
|
|
| H |
asthma |
Lung |
mice |
Reference
10984054 |
C3a receptor |
knockout |
|
|
|
|
|
|
|
| H |
asthma |
Lung |
mice |
Reference
9476873 |
ET-1 |
knockout |
|
|
|
|
|
|
|
| H |
asthma |
Lung |
mice |
Reference
9182686'); |
interleukin-5 (IL-5) |
transgenic |
|
|
|
|
|
|
|
| H |
asthma |
Lung |
mice |
Reference
11781348'); |
interleukin-9 (IL-9) |
transgenic |
|
|
|
|
|
|
|
| H |
asthma |
Lung |
mice |
Reference
11070175'); |
interleukin-9 (IL-9) |
knockout |
|
|
|
|
|
|
|
| H |
asthma |
Lung |
mice |
Reference
10589010'); |
interleukin-12(IL-12);interferon-gamma |
knockout |
|
|
|
|
|
|
|
| H |
asthma |
Lung |
mice |
Reference
9802985'); |
NF-kappaB p50 subunit |
knockout |
|
|
|
|
|
|
|
| H |
asthma |
Lung |
mice |
Reference
9009274'); |
platelet-activating factor receptor (PAFR) |
transgenic |
|
|
|
|
|
|
|
| H |
asthma |
Lung |
mice |
Reference
11000125'); |
RANTES |
transgenic |
|
|
|
|
|
|
|
| LM |
Asthma |
|
monkeys |
Reference 8368159 |
|
|
|
|
|
|
|
|
|
| A |
Asthma |
|
dogs |
15th Fascicle, AFIP, 1986 |
|
|
|
|
|
|
|
|
| H |
asthma / lung eosinophilia |
Lung |
mice |
Reference
9808585 |
eotaxin |
knockout |
|
|
|
|
|
|
|
| H |
asthma, airway hyperresponsiveness |
Lung |
mice |
Reference
10330441'); |
NOS-3 |
transgenic |
|
|
|
|
|
|
|
| LM |
astrocytomas |
|
monkey, Aotus trivirgatus |
Reference 6304759 |
|
|
|
|
|
|
|
|
|
| H |
atherogenesis |
Heart |
mice |
Reference
8798642 |
12-lipoxygenase (L-12LO), leukocyte-type |
knockout by homologous recombination in embryonic |
|
|
|
|
|
|
|
| H |
atherogenesis |
Heart |
mice |
Reference |
12-lipoxygenase (L-12LO), leukocyte-type |
knockout by homologous
recombination in embryonic stem cells |
|
|
|
|
|
|
| H |
atherogenesis |
Heart |
mice |
Reference
7860728 |
apolipoprotein E (apoE) |
transgenic |
|
|
|
|
|
|
|
| H |
atherogenesis |
Heart |
mice |
Reference
7607230'); |
lecithin: cholesterol acyltransferase (LCAT) |
transgenic |
|
|
|
|
|
|
|
| LM |
atherosclerosis |
|
baboons |
Reference 179299 |
|
|
|
|
|
|
|
|
|
| LM |
atherosclerosis |
|
chimpanzee |
Reference 179299 |
|
|
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference |
5-Lipoxygenase (5-LO) |
knockout x LDLR (-/-) |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference |
ABCA1 (ATP-binding cassette transporter 1) |
bone marrow transfer |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
9520126 |
apolipoprotein (a) |
other: site-directed mutagenesis |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
9884386 |
apolipoprotein (apo) A-I |
somatic gene transfer |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
11031214 |
apolipoprotein A-I/C-III/A-IV gene cluster |
transgenic |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
9539774'); |
LDL receptor; apoB; apoA; LDLR-/-; Tg(apoB+/+); Tg(apoa+/-) |
knockout, transgenic |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
9212100'); |
lecithin-cholesteryl acyltransferase (LCAT) |
transgenic |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
10744772'); |
lipoprotein lipase (LPL) and apoE(-/-) |
transgenic heterozygote LDL (+/-) plus apoE(-/-) |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
11342477'); |
lipoxygenase (12/15-LO) |
double knockout |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
8692976'); |
low-density lipoprotein receptor knockout plus lipoprotein lipase overexpression (LPL/LDLRKO) |
transgenic, knockout |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
11701470'); |
LPL (lipoprotein lipase) |
transgenic macrophage expression |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
9564887'); |
macrophage scavenger receptors (MSR-A); LDL receptor |
double knockout |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
12234960'); |
MINOR (mitogen-induced nuclear orphan receptor) |
transgenic |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
12135950'); |
paraoxonase (PON1) |
transgenic |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
10748217'); |
paraoxonase (PON1) KO / apoE KO |
double knockout |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
mice |
Reference
10764677'); |
phospholipid transfer protein (PLTP) |
transgenic overexpression |
|
|
|
|
|
|
|
| LM |
atherosclerosis |
|
mice |
Reference |
|
|
|
|
|
|
|
|
|
| LM |
atherosclerosis |
|
mice |
Reference |
|
|
|
|
|
|
|
|
|
| LM |
atherosclerosis |
|
monkey |
Reference 47486 |
|
|
|
|
|
|
|
|
|
| LM |
atherosclerosis |
|
monkey, fascicularis |
Reference 7457569 |
|
|
|
|
|
|
|
|
|
| LM |
atherosclerosis |
|
monkey, macaca |
Reference 5006016 |
|
|
|
|
|
|
|
|
|
| LM |
atherosclerosis |
|
monkey, macaca mulatta |
Reference 179299 |
|
|
|
|
|
|
|
|
|
| LM |
atherosclerosis |
|
monkey, macaca mulatta, fascicularis |
Reference 414525 |
|
|
|
|
|
|
|
|
|
| LM |
atherosclerosis |
|
monkey, macaca mulatta, fascicularis |
Reference 813205 |
|
|
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
rabbit |
Reference
11795291'); |
lipoprotein (a) [Lp(a)] |
transgenic |
|
|
|
|
|
|
|
| H |
atherosclerosis |
Heart |
rabbit |
Reference
12149463'); |
uPA (urokinase plasminogen activator) |
targeted expression in carotid arteries |
|
|
|
|
|
|
|
| A |
Atherosclerosis |
|
chickens |
16th Fascicle, AFIP, 1987 |
|
|
|
|
|
|
|
|
| H |
atherosclerosis and immunity |
Heart |
mice |
Reference
9114044 |
apolipoprotein E (apoE)-deficient crossed with recombinase activating gene 1 (Rag-1) knockout |
double knockout |
|
|
|
|
|
|
|
| H |
atherosclerosis, cardiac disease, stroke |
Heart |
mice |
Reference
7585043 |
apolipoprotein (a) |
transgenic |
|
|
|
|
|
|
|
| H |
atherosclerosis, ischemic reperfusion |
Heart |
mice |
Reference
10859290'); |
thromboxane receptor TP-beta |
transgenic targeted vasculature overexpression |
|
|
|
|
|
|
|
| H |
atherosclerosis; familial combined hyperlipidemia |
Heart |
mice |
Reference
8994037 |
apolipoprotein C-III (APOC3) x low density lipoprotein (LDL) receptor |
transgenic APOC3 x LDL receptor knockout |
|
|
|
|
|
|
|
| H |
atherosclerosis; restenosis |
Heart |
mice |
Reference
12114325'); |
osteopontin |
transgenic overexpression |
|
|
|
|
|
|
|
| H |
atherosclerosis; vascular diseases |
Heart |
mice |
Reference
8689409'); |
platelet derived growth factor receptor |
transgenic |
|
|
|
|
|
|
|
| H |
atrial fibrosis |
Heart |
mice |
Reference
10720419'); |
transforming growth factor (TGF)-beta(1) |
transgenic cardiac-specific |
|
|
|
|
|
|
|
| A |
Atrial Thrombosis |
|
hamsters |
11th Fascicle, AFIP, 1982 |
|
|
|
|
|
|
|
|
| H |
atrioventricular canal-specific expression in embryonic
development |
Heart |
mice |
Reference
10985429'); |
troponin I, cardiac |
transgenic |
|
|
|
|
|
|
|
| A |
Aural Cholesteatoma |
|
gerbils |
15th Fascicle, AFIP, 1986 |
|
|
|
|
|
|
|
|
| H |
autoimmune (anti-DNA) diseases |
Blood |
mice |
Reference
9300728'); |
protein-tyrosine phosphatases HCP and SHP-1 |
other |
|
|
|
|
|
|
|
| A |
Autoimmune Disease |
|
mice |
3rd Fascicle, AFIP, 1974: |
|
|
|
|
|
|
|
|
| H |
autoimmune nephritis |
Blood |
mice |
Reference
9862739'); |
terminal deoxynucleotidyl transferase |
knockout |
|
|
|
|
|
|
|
| H |
autoimmune thyroiditis |
Blood |
mice |
Reference
8640878'); |
T cell receptor |
transgenic and other |
|
|
|
|
|
|
|
| A |
Autoimmune Thyroiditis |
|
Mastomys |
14th Fascicle, AFIP, 1985 |
|
|
|
|
|
|
|
|
| A |
Autoimmune Thyroiditis |
|
rats |
11th Fascicle, AFIP, 1982 |
|
|
|
|
|
|
|
|
| M |
Autoimmunity/
Cardiovascular/ Immunology and Inflammation /Immunodeficiency /Research Tools / Virology |
mice |
Igh-6 |
C.129S2(B6)-Igh-6tm1Cgn/Hsd |
Targeted Mutation / Knockout |
MMRRC:0205-H/M |
MMRRC Catalog |
Cryopreserved |
|
|
|
|
| MM |
Autoimmunity/
Cardiovascular/ Immunology and Inflammation /Immunodeficiency /Research Tools / Virology |
mice |
Igh-6 |
Igh-6 |
Targeted Mutation / Knockout |
MMRRC:0205-H/M |
MMRRC Catalog |
C.129S2(B6)-Igh-6tm1Cgn/Hsd |
Cryopreserved |
|
|
|
| A |
Autosomal
Trisomy, Developmental Impairment and Fetal Death |
|
mice |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| H |
B and T cell development |
Blood |
mice |
Reference
8543797 |
heat-stable antigen |
transgenic |
|
|
|
|
|
|
|
| H |
B cell development |
Blood |
mice |
Reference
9317126 |
CD19 |
knockout |
|
|
|
|
|
|
|
| H |
B cell development |
Blood |
mice |
Reference
10733501 |
CD69 |
knockout |
|
|
|
|
|
|
|
| H |
B cell development |
Blood |
mice |
Reference
10403484'); |
NF-kappaB |
transgenic |
|
|
|
|
|
|
|
| LM |
B virus |
|
rabbits |
Reference 193814 |
|
|
|
|
|
|
|
|
|
| LM |
B19 parovirus infection |
|
monkeys, cynomolgus macaques |
Reference 8163659 |
|
|
|
|
|
|
|
|
|
| A |
Babesiosis |
|
hamsters. |
17th Fascicle, AFIP, 1989 |
|
|
|
|
|
|
|
|
| A |
Bacillary Dysentery,
Shigellosis |
|
monkeys |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| LM |
bacterial disease |
|
monkey |
Reference 6395673 |
|
|
|
|
|
|
|
|
|
| A |
Bacterial Endocarditis |
|
opossum |
1st Fascicle, AFIP, 1972: |
|
|
|
|
|
|
|
|
| LM |
bacterial sepsis |
|
monkey, macaca mulatta |
Reference 98603 |
|
|
|
|
|
|
|
|
|
| A |
Baldness |
|
macaques |
10th Fascicle, AFIP, 1981 |
|
|
|
|
|
|
|
|
| A |
Bancroftian Filariasis |
|
monkeys |
13th Fascicle, AFIP, 1984 |
|
|
|
|
|
|
|
|
| LM |
bancroftian filiariasis |
|
monkey, leaf |
Reference 7046076 |
|
|
|
|
|
|
|
|
|
| LM |
bancroftian filiariasis |
|
monkey, leaf |
Reference 6805349 |
|
|
|
|
|
|
|
|
|
| LM |
bancroftian filiariasis |
|
monkey, silver leaf |
Reference 3312807 |
|
|
|
|
|
|
|
|
|
| H |
B-cell development and immune function |
Blood |
mice |
Reference
10648608 |
B-cell lymphocyte kinase |
knockout |
|
|
|
|
|
|
|
| D |
Behavior |
|
Monkey, African Green Monkey |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| D |
Behavior |
|
Monkey, Marmosets |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| A |
Benign Monoclonal
Gammopathy |
|
mice |
11th Fascicle, AFIP, 1982 |
|
|
|
|
|
|
|
|
| H |
Bernard-Soulier syndrome |
Blood |
mice |
Reference
10706630'); |
platelet glycoprotein Ib-IX-V (alpha) |
knockout |
|
|
|
|
|
|
|
| H |
beta zero thalassemia |
Blood |
mice |
Reference
7568113 |
hemoglobin, beta chain |
knockout |
|
|
|
|
|
|
|
| H |
beta zero thalassemia |
Blood |
mice |
Reference
8524813 |
hemoglobin, beta chain |
other |
|
|
|
|
|
|
|
| H |
beta-adrenergic receptor desensitization in heart |
Heart |
mice |
Reference
8790438 |
G protein-coupled receptor kinase-5 (GRK-5) |
transgenic |
|
|
|
|
|
|
|
| H |
beta-adrenergic receptor dysfunction;cardiac hypertrophy |
Heart |
mice |
Reference |
adenylyl cyclase type V x G alpha q |
double transgenic overexpression |
|
|
|
|
|
|
|
| LM |
beta-hemolytic streptococcic infections |
|
chimpanzee |
Reference 5452082 |
|
|
|
|
|
|
|
|
|
| H |
beta-thalassemia |
DBDR |
mice |
Reference
11342459 |
gamma-globin |
transgenic |
|
|
|
|
|
|
|
| A |
Beta-Thalassemia |
|
mice |
19th Fascicle, AFIP, 1993 |
|
|
|
|
|
|
|
|
| A |
Bioprosthetic Cardiac
Valves |
|
sheep |
11th Fascicle, AFIP, 1982 |
|
|
|
|
|
|
|
|
| H |
blood and marrow transplantation |
Blood |
mice |
Reference
11141477 |
green fluorescent protein |
transgenic |
|
|
|
|
|
|
|
| H |
blood pressure |
Heart |
mice |
Reference
10642343 |
alpha-calcitonin gene-related peptide (alpha-CGRP) |
knockout |
|
|
|
|
|
|
|
| H |
blood pressure |
Heart |
mice |
Reference
10098521'); |
PTH-related protein receptor |
transgenic overexpression |
|
|
|
|
|
|
|
| H |
blood pressure; central nervous system functions |
Heart |
mice |
Reference
7477266 |
angiotensin II type-2 receptor (AT2) |
knockout |
|
|
|
|
|
|
|
| H |
blood pressure; central nervous system functions |
Heart |
mice |
Reference
7477267 |
angiotensin II type-2 receptor (AT2) |
knockout |
|
|
|
|
|
|
|
| H |
blood pressure; growth; kidney structure |
Heart |
mice |
Reference
9860997 |
angiotensin II receptors AT1A and AT1B |
knockout |
|
|
|
|
|
|
|
| M |
Blood vessel development |
|
mice |
Edg1 |
B6;129S-Edg1tm1Rlp/Unc |
Targeted Mutation / Knockout |
MMRRC:0035-UNC |
MMRRC Catalog |
Live Colony |
|
|
|
|
| MM |
Blood vessel development |
|
mice |
Edg1 |
Edg1 |
Targeted Mutation / Knockout |
MMRRC:0035-UNC |
MMRRC Catalog |
B6;129S-Edg1tm1Rlp/Unc |
Live Colony |
|
|
|
| H |
bone marrow transplantation |
Blood |
mice |
Reference
9223319'); |
killer cell inhibitory receptor |
transgenic |
|
|
|
|
|
|
|
| A |
Bovine
Leukocyte Adhesion Deficiency: ß2 Integrin Deficiency |
|
Holstein cattle |
19th Fascicle, AFIP, 1993 |
|
|
|
|
|
|
|
|
| H |
bradycardia, ventricular failure |
Heart |
mice |
Reference
10377168'); |
RhoA |
transgenic overexpression |
|
|
|
|
|
|
|
| H |
bradycardia; arrhythmia |
Heart |
mice |
Reference
10929716 |
calcium channels, class D L-type (D-LTCC) |
knockout |
|
|
|
|
|
|
|
| A |
Breast Cancer |
|
cats |
9th Fascicle, AFIP, 1980 |
|
|
|
|
|
|
|
|
| A |
Breast Cancer |
|
dog |
4th Fascicle, AFIP, 1975 |
|
|
|
|
|
|
|
|
| A |
Bronchiolo-Alveolar
Cell Carcinoma |
|
sheep |
8th Fascicle, AFIP, 1979 |
|
|
|
|
|
|
|
|
| A |
Bronchogenic Carcinoma |
|
hamsters |
9th Fascicle, AFIP, 1980 |
|
|
|
|
|
|
|
|
| LM |
Brugia malayi |
|
monkey, bush baby |
Reference 809564 |
|
|
|
|
|
|
|
|
|
| H |
Brugia malayi infection |
Blood |
mice |
Reference
7776141'); |
immunoglobulin M |
knockout |
|
|
|
|
|
|
|
| LM |
Burkitt lymphoma |
|
monkey, Aotus trivirgatus |
Reference 4209602 |
|
|
|
|
|
|
|
|
|
| H |
burn injury |
Blood |
mice |
Reference
9706148'); |
T cell receptor |
transgenic |
|
|
|
|
|
|
|
| LM |
Cadmium Toxicosis |
|
Cynomolgus macaques |
Reference 12675553 |
|
|
|
|
|
|
|
|
|
| A |
Calcitonin-secreting
Medullary Thyroid Carcinoma |
|
bovine |
3rd Fascicle, AFIP, 1974: |
|
|
|
|
|
|
|
|
| LM |
Calcium pyrophosphate deposition |
|
monkey, macaca mulatta |
Reference 6087670 |
|
|
|
|
|
|
|
|
|
| A |
Calcium
Pyrophosphate Deposition Disease |
|
monkeys |
14th Fascicle, AFIP, 1985 |
|
|
|
|
|
|
|
|
| A |
Campylobacter Enteritis |
|
rabbits |
15th Fascicle, AFIP, 1986 |
|
|
|
|
|
|
|
|
| LM |
Campylobacter Infections |
|
monkey, macaca mulatta |
Reference 3371715 |
|
|
|
|
|
|
|
|
|
| LM |
Campylobacter pylori |
|
monkey, nemestrina |
Reference 3183019 |
|
|
|
|
|
|
|
|
|
| LM |
Campylobacter-like organisms |
|
monkey, macaca mulatta |
Reference 3172170 |
|
|
|
|
|
|
|
|
|
| LM |
cancer |
|
cat |
Reference 4363397 |
|
|
|
|
|
|
|
|
|
| LM |
cancer |
|
cattle |
Reference 4363397 |
|
|
|
|
|
|
|
|
|
| LM |
cancer |
|
monkey |
Reference 4363397 |
|
|
|
|
|
|
|
|
|
| LM |
Cancer |
|
monkey, macaca |
Reference 4366898 |
|
|
|
|
|
|
|
|
|
| LM |
cancer |
|
monkey, marmoset |
Reference 417316 |
|
|
|
|
|
|
|
|
|
| LM |
cancer, colon |
|
cotton-top tamarin |
Reference 8536845 |
|
|
|
|
|
|
|
|
|
| LM |
cancer, colon |
|
monkey, tamarins |
Reference 2493193 |
|
|
|
|
|
|
|
|
|
| LM |
Cancer, Nasal |
|
monkeys |
Reference 8137081 |
|
|
|
|
|
|
|
|
|
| LM |
Cancer, Nasal |
|
monkeys |
Reference 8137082 |
|
|
|
|
|
|
|
|
|
| LM |
Canine distemper virus |
|
monkey, squirrel |
Reference 2338709 |
|
|
|
|
|
|
|
|
|
| A |
Canine Struvite
Urolithiasis |
|
dogs |
10th Fascicle, AFIP, 1981 |
|
|
|
|
|
|
|
|
| A |
Carcinogenesis
in the Uterine Cervix |
|
mice |
7th Fascicle, AFIP, 1978 |
|
|
|
|
|
|
|
|
| A |
Carcinoids
and Adenocarcimnoma of the Stomach |
|
Mastomys |
9th Fascicle, AFIP, 1980 |
|
|
|
|
|
|
|
|
| A |
Carcinoma of the
Urinary Bladder |
|
rats |
9th Fascicle, AFIP, 1980 |
|
|
|
|
|
|
|
|
| H |
cardiac abnormalities |
Heart |
mice |
Reference
9737941 |
beta-tropomyosin |
transgenic overexpression |
|
|
|
|
|
|
|
| H |
cardiac allograft rejection |
Heart |
mice |
Reference
11544273 |
fractalkine receptor CX(3)CR1 |
targeted disruption |
|
|
|
|
|
|
|
| H |
cardiac allograft rejection |
Heart |
mice |
Reference
11901205'); |
LIGHT |
knockout |
|
|
|
|
|
|
|
| H |
cardiac beta-adrenergic stimulation |
Heart |
mice |
Reference |
adenylylcyclase |
transgenic (cardiac-directed) |
|
|
|
|
|
|
|
| H |
cardiac contractile dysfunction, cardiac morphogenesis |
Heart |
mice |
Reference
11331753'); |
vascular endothelial growth factor |
cardiac myocyte-specific knockout |
|
|
|
|
|
|
|
| H |
cardiac contractile failure |
Heart |
mice |
Reference
11328820'); |
phospholamban |
transgenic overexpression |
|
|
|
|
|
|
|
| H |
cardiac contractility |
Heart |
mice |
Reference |
adenylyl cyclase type8 (AC8), Ca(2+)-stimulated |
transgenic cardiac-specific expression |
|
|
|
|
|
|
|
| H |
cardiac contractility |
Heart |
mice |
Reference
11509451 |
alpha(1A)-adrenergic receptor (alpha(1A)-AR) |
cardiac-specific overexpression |
|
|
|
|
|
|
|
| H |
cardiac contractility |
Heart |
mice |
Reference
11705829 |
beta(3)-adrenergic receptors [beta(3) AR] |
transgenic cardiac overexpression |
|
|
|
|
|
|
|
| H |
cardiac contractility |
Heart |
mice |
Reference
10744747'); |
phospholamban |
transgenic cardiac-specific overexpression |
|
|
|
|
|
|
|
| H |
cardiac contractility |
Heart |
mice |
Reference
9314829'); |
phospholamban, monomeric (Cys41Phe) or (Cys41 --> Phe41) |
transgenic cardiac overexpression |
|
|
|
|
|
|
|
| H |
cardiac contractility |
Heart |
mice |
Reference
9797337'); |
sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA1a) |
transgenic overexpression |
|
|
|
|
|
|
|
| H |
cardiac contractility |
Heart |
mice |
Reference
9218515'); |
sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) |
transgenic overexpression |
|
|
|
|
|
|
|
| H |
cardiac contractility response to hemodynamic stress |
Heart |
mice |
Reference
11909974'); |
S100A1 |
targeted deletion |
|
|
|
|
|
|
|
| H |
cardiac development |
Heart |
mice |
Reference
10811845 |
endothelin converting enzyme (ECE)-2 |
knockout |
|
|
|
|
|
|
|
| H |
cardiac development;cardiac myocyte metabolism |
Heart |
mice |
Reference
11877471'); |
insulin receptor in cardiomyocyte (CIR) |
cardiomyocyte selective knockout |
|
|
|
|
|
|
|
| H |
cardiac function |
Heart |
mice |
Reference
11717159'); |
K(ATP) channel subunit Kir6.2 |
transgenic |
|
|
|
|
|
|
|
| H |
cardiac function, heart failure |
Heart |
mice |
Reference
12024026'); |
phosphatase, type 1 (PP1) |
targeted overexpression of catalytic subunit |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy |
Heart |
mice |
Reference
11551931 |
angiotensin II |
transgenic expression in cardiac myocytes |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy |
Heart |
mice |
Reference
10639182 |
angiotensin II type 1 receptor (AT1R) |
cardiomyocyte-specific overexpression |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy |
Heart |
mice |
Reference
11739276 |
c-Myc |
transgenic expression in cardiac myocytes |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy |
Heart |
mice |
Reference
9568714 |
calcineurin |
transgenic |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy |
Heart |
mice |
Reference
10756124 |
calcineurin (PP2B) |
transgenic |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy |
Heart |
mice |
Reference
9774476 |
calsequestrin |
transgenic overexpression |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy |
Heart |
mice |
Reference
11023666 |
gp130 |
transgenic |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy |
Heart |
mice |
Reference
9927691'); |
human myosin essential light chain |
transgenic |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy |
Heart |
mice |
Reference
11101507'); |
MEK1 |
transgenic expression in heart |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy |
Heart |
mice |
Reference
11485548'); |
ornithine decarboxylase (ODC) |
cardiac-specific overexpression |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy |
Heart |
rat |
Reference
11692158 |
AT1 receptor (Angiotensin II type 1 receptor) |
transgenic expression in myocardium |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy (lack of) |
Heart |
mice |
Reference
9261135 |
alpha 1B-adrenergic receptor (AR), wild type |
transgenic cardiac overexpression |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy in adults, sudden death in neonates |
Heart |
mice |
Reference
9410895'); |
protein kinase C beta |
transgenic, conditional expression in cardiomyocyt |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy in adults, sudden death in neonates |
Heart |
mice |
Reference
9410895'); |
protein kinase C beta |
transgenic, conditional expression in cardiomyocytes |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy without hypertension |
Heart |
mice |
Reference
9622149 |
angiotensinogen targeted to heart |
transgenic overexpression of angiotensinogen |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy, cardiac dilatation, sudden death |
Heart |
mice |
Reference
11943770 |
Akt |
cardiac-specific transgenic overexpression |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy, fibrosis, function |
Heart |
mice |
Reference
11238056'); |
integrin |
trangenic expression in cardiac myocyte |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy; cardiomyocyte degeneration; gene
reprogramming |
Heart |
mice |
Reference
10445845'); |
leukocyte tyrosine kinase |
transgenic, heart-specific activation |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy; heart failure |
Heart |
mice |
Reference
10359838 |
beta1-adrenergic receptor |
transgenic |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy;heart failure |
Heart |
mice |
Reference
11782539 |
glycogen synthase kinase-3 (GSK-3) |
cardiac specific transgenic |
|
|
|
|
|
|
|
| H |
cardiac hypertrophy;heart failure |
Heart |
mice |
Reference
11739277'); |
Rab1a |
transgenic overexpression in heart |
|
|
|
|
|
|
|
| H |
cardiac inflammation, hypertrophy |
Heart |
mice |
Reference
10791994 |
Fas ligand (FasL) |
transgenic targeted expression to heart |
|
|
|
|
|
|
|
| H |
cardiac ischemia; dilated cardiomyopathy |
Heart |
mice |
Reference |
adenosine receptor A3AR |
cardiac-specific overexpression |
|
|
|
|
|
|
|
| H |
cardiac lipid accumulation |
Heart |
mice |
Reference
11551864'); |
hormone-sensitive lipase (HSL) |
heart-specific overexpression |
|
|
|
|
|
|
|
| H |
cardiac malformation |
Heart |
mice |
Reference
11572777'); |
T-box transcription factor (Tbx5) |
knockout, heterozygous |
|
|
|
|
|
|
|
| H |
cardiac myocyte development, tetralogy of Fallot, double
outlet right ventricle |
Heart |
mice |
Reference
9356462'); |
nonmuscle myosin heavy chain B (NMHC-B) |
knockout |
|
|
|
|
|
|
|
| H |
cardiac myocyte growth during cardiogenesis |
Heart |
mice |
Reference
10425189'); |
TREB5 |
knockout |
|
|
|
|
|
|
|
| H |
cardiac pathology |
Heart |
mice |
Reference
10399364 |
essential myosin light chain 1v |
transgenic overexpression |
|
|
|
|
|
|
|
| H |
cardiac remodeling,atrial fibrillation |
Heart |
mice |
Reference
12154005'); |
Junctin |
transgenic overexpression |
|
|
|
|
|
|
|
| H |
cardiac sarcoplasmic reticulum, function of calcium pump in |
Heart |
mice |
Reference
10766848'); |
phospholamban, non-phosphorylatable (S16A,T17A) |
targeted expression to heart |
|
|
|
|
|
|
|
| H |
cardiac twitch dynamics |
Heart |
mice |
Reference
11934831 |
cTnI (cardiac troponin I) |
transgenic, mutation |
|
|
|
|
|
|
|
| H |
cardiac-specific expression |
Heart |
mice |
Reference
10988285'); |
phospholamban PLBS16A/PLBT17A |
transgenic |
|
|
|
|
|
|
|
| H |
cardiogenesis |
Heart |
mice |
Reference
9895330'); |
Nkx2-5 flanking sequences |
transgenic |
|
|
|
|
|
|
|
| H |
cardiomegaly, myocyte proliferation |
Heart |
mice |
Reference
8710922'); |
insulin-like growth factor 1B (IGF-1B) |
transgenic |
|
|
|
|
|
|
|
| H |
cardiomyocyte differentiation |
Heart |
mice |
Reference
9876177 |
Cripto protein (tdgf1) |
knockout |
|
|
|
|
|
|
|
| H |
cardiomyocyte formation |
Heart |
cultured embryonic stem cells |
Reference
9576836 |
growth factor Cripto-1 (Cr-1) |
homologous recombination |
|
|
|
|
|
|
|
| H |
cardiomyocyte structure and function |
Heart |
mice |
Reference
11123252'); |
integrin,alpha(5-1) |
transgenic expression in cardiomyocytes |
|
|
|
|
|
|
|
| H |
cardiomyopathy |
Heart |
mice |
Reference
9916807'); |
mitochondrial transcription factor A (Tfam, previously mtTFA) |
conditional mutation |
|
|
|
|
|
|
|
| H |
cardiomyopathy |
Heart |
mice |
Reference
10737799'); |
mitochondrial transcription factor A (Tfam, also called mtTFA) |
knockout, temporal and tissue specific |
|
|
|
|
|
|
|
| H |
cardiomyopathy |
Heart |
mice |
Reference
11171800'); |
phospholamban |
transgenic |
|
|
|
|
|
|
|
| H |
cardiomyopathy |
Heart |
mice |
Reference
11247792'); |
serum response factor (SRF) |
cardiac-specific overexpression |
|
|
|
|
|
|
|
| H |
cardiomyopathy |
Heart |
mice |
Reference
9421465'); |
tropomodulin |
transgenic |
|
|
|
|
|
|
|
| A |
Cardiomyopathy |
|
hamster |
2nd Fascicle, AFIP, 1973: |
|
|
|
|
|
|
|
|
| A |
Cardiomyopathy |
|
turkeys |
4th Fascicle, AFIP, 1975 |
|
|
|
|
|
|
|
|
| H |
cardiomyopathy associated with doxorubicin treatment |
Heart |
mice |
Reference
11016643 |
carbonyl reductase |
cardiac-specific expression |
|
|
|
|
|
|
|
| H |
cardiomyopathy, hypertrophy and dilation in |
Heart |
mice |
Reference
10727657 |
calcineurin/tropomodulin |
transgenic cross-breeding |
|
|
|
|
|
|
|
| H |
cardiomyopathy, loss of ventricular mass |
Heart |
mice |
Reference
11413089'); |
serotonin 5-HT(2B) |
knockout |
|
|
|
|
|
|
|
| H |
cardiomyopathy; cardiac hypertrophy; heart failure |
Heart |
mice |
Reference
9039266'); |
MLP |
knockout |
|
|
|
|
|
|
|
| H |
cardiomyopathy;bradyarrhythmia;sudden cardiac death |
Heart |
mice |
Reference
11901182'); |
iNOS |
cardiomyocyte overexpression |
|
|
|
|
|
|
|
| A |
Cardiopulminary
Disease, Endocardial Fibroelastosis |
|
monkey |
3rd Fascicle, AFIP, 1974: |
|
|
|
|
|
|
|
|
| D |
Cardiovascular |
|
Baboons |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| H |
cardiovascular development |
Heart |
mice |
Reference
10191047 |
connexin 43 |
other (targeted expression in neural crest) |
|
|
|
|
|
|
|
| LM |
cardiovascular disease |
|
monkey, macaca |
Reference 5006016 |
|
|
|
|
|
|
|
|
|
| LM |
cardiovascular disease |
|
monkey, macaca mulatta |
Reference 810588 |
|
|
|
|
|
|
|
|
|
| M |
cardiovascular disease/
Osteoporosis / mouse models of human disease |
mice |
Esr2 |
B6.129P2-Esr2tm1Unc |
Targeted Mutation / Knockout |
MMRRC:0002-UNC |
MMRRC Catalog |
Live Colony,Non-Profit Only** |
|
|
|
|
| MM |
cardiovascular disease/
Osteoporosis / mouse models of human disease |
mice |
Esr2 |
Esr2 |
Targeted Mutation / Knockout |
MMRRC:0002-UNC |
MMRRC Catalog |
B6.129P2-Esr2tm1Unc |
Live Colony,Non-Profit
Only** |
|
|
| M |
Cardiovascular diseases/ Diabetes/ Inflammation / bone matrix
biology |
|
mice |
Gulo |
B6.129P2-Gulotm1Unc/Ucd |
Targeted Mutation / Knockout |
MMRRC:0015-UCD |
MMRRC Catalog |
Live Colony |
|
|
|
|
| MM |
Cardiovascular diseases/ Diabetes/ Inflammation / bone matrix
biology |
|
mice |
Gulo |
Gulo |
Targeted Mutation / Knockout |
MMRRC:0015-UCD |
MMRRC Catalog |
B6.129P2-Gulotm1Unc/Ucd |
Live Colony |
|
|
|
| M |
cardiovascular/ cancer
research / Diabetes/ mouse models of human disease |
mice |
Fga,
Fgb, Fgg |
C57BL/6J-Tg(FgaFgbFgg)1Unc |
Transgenic |
MMRRC:0001-UNC |
MMRRC Catalog |
Live Colony, Non-Profit Only** |
|
|
|
|
| MM |
cardiovascular/ cancer
research / Diabetes/ mouse models of human disease |
mice |
Fga,
Fgb, Fgg |
Fga,
Fgb, Fgg |
Transgenic |
MMRRC:0001-UNC |
MMRRC Catalog |
C57BL/6J-Tg(FgaFgbFgg)1Unc |
Live Colony, Non-Profit
Only** |
|
|
| D |
Cardiovascular/pulmonary disorder |
|
Monkey, African Green Monkey |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| LM |
Cartiledge diseases |
|
monkey, macaca mulatta |
Reference 6087670 |
|
|
|
|
|
|
|
|
|
| LM |
CDV, Caninine distemper virus |
|
monkey, squirrel |
Reference 2338709 |
|
|
|
|
|
|
|
|
|
| D |
Cell biology |
|
Monkey, African Green Monkey |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| H |
cellular longevity |
Blood |
mice |
Reference
10357808'); |
telomerase RNA |
knockout |
|
|
|
|
|
|
|
| D |
Central Nervous Systems |
|
Monkey, Squirrel Monkeys |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| H |
cerebral artery dilation |
Heart |
mice |
Reference
10904001'); |
K(+) currents, inward rectifying (Kir2.1), (Kir2.2) |
knockouts |
|
|
|
|
|
|
|
| LM |
Cerebral athero-arteriosclerotic lesions |
|
monkey, macaca mulatta |
Reference 6605917 |
|
|
|
|
|
|
|
|
|
| A |
Cerebral
Calcification, Cytomegalovirus Infection |
|
mice |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| LM |
Cerebral cortical atrophy |
|
baboons |
Reference 3727320 |
|
|
|
|
|
|
|
|
|
| A |
Cerebral Infarction |
|
rats |
18th Fascicle, AFIP, 1991 |
|
|
|
|
|
|
|
|
| H |
cerebral ischemia |
Heart |
mice |
Reference
11231631 |
fibronectin plasma (pFn) |
conditional knockout |
|
|
|
|
|
|
|
| H |
cerebral ischemia and reperfusion |
Heart |
rat |
Reference
9763473'); |
superoxide dismutase1 (SOD1) |
transgenic overexpression |
|
|
|
|
|
|
|
| H |
cerebral malaria |
Blood |
mice |
Reference
9864254'); |
T cell receptor, gamma-delta |
knockout |
|
|
|
|
|
|
|
| A |
Ceroid-Lipofuscinosis |
|
dogs and sheep |
9th Fascicle, AFIP, 1980 |
|
|
|
|
|
|
|
|
| A |
Chagas' Disease |
|
rabbits |
15th Fascicle, AFIP, 1986 |
|
|
|
|
|
|
|
|
| A |
Chédiak-Higashi Syndrome |
|
several species |
7th Fascicle, AFIP, 1978 |
|
|
|
|
|
|
|
|
| LM |
Chickenpox |
|
monkey, macaca |
Reference 6098169 |
|
|
|
|
|
|
|
|
|
| LM |
Chickenpox |
|
monkeys, African green |
Reference 8509658 |
|
|
|
|
|
|
|
|
|
| LM |
Chlamdia trachomatis |
|
monkey, Aotus trivirgatus |
Reference 828229 |
|
|
|
|
|
|
|
|
|
| D |
Chlamydia trachomatis Infections |
|
Monkey, Pigtailed Macaques |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| A |
Chlamydial
Genital Tract Infections |
|
nonhuman primates |
11th Fascicle, AFIP, 1982 |
|
|
|
|
|
|
|
|
| A |
Cholangiocarcinoma |
|
hamsters |
12th Fascicle, AFIP, 1983 |
|
|
|
|
|
|
|
|
| A |
Cholelithiasis |
|
monkeys |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| A |
Cholelithiasis |
|
squirrels |
17th Fascicle, AFIP, 1989 |
|
|
|
|
|
|
|
|
| A |
Chordoma |
|
ferrets |
20th Fascicle, AFIP, 1995 |
|
|
|
|
|
|
|
|
| A |
Chronic Beryllium Lung
Disease |
|
dogs |
20th Fascicle, AFIP, 1995 |
|
|
|
|
|
|
|
|
| A |
Chronic Biliary
Obstruction |
|
mice |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| A |
Chronic Bronchitis |
|
dogs |
9th Fascicle, AFIP, 1980 |
|
|
|
|
|
|
|
|
| A |
Chronic Bronchitis |
|
pigs |
6th Fascicle, AFIP, 1977 |
|
|
|
|
|
|
|
|
| H |
chronic colitis |
Blood |
mice |
Reference
9449719'); |
interleukin-7 (IL-7) |
transgenic |
|
|
|
|
|
|
|
| H |
chronic enterocolitis |
Blood |
mice |
Reference
10023769 |
Stat3 |
knockout |
|
|
|
|
|
|
|
| H |
chronic hepatitis B infection |
Blood |
mice |
Reference
11145724 |
hepatitis B genome |
transgenic |
|
|
|
|
|
|
|
| H |
chronic hepatitis B infection |
Blood |
mice |
Reference
10906213'); |
T-cell receptor (hepatitis B e antigen) |
transgenic |
|
|
|
|
|
|
|
| A |
Chronic Pulminary
Hypertension |
|
rats |
8th Fascicle, AFIP, 1979 |
|
|
|
|
|
|
|
|
| A |
Cigarette
Smoke Induced Laryngeal Carcinoma |
|
hamsters |
9th Fascicle, AFIP, 1980 |
|
|
|
|
|
|
|
|
| H |
circadian mutant |
Sleep |
mice |
Reference
11425915'); |
PAC1 (pituitary adenylate cyclase activating polypeptide type 1 receptor) |
knockout |
|
|
|
|
|
|
|
| H |
circadian mutant |
Sleep |
mice |
Reference
11483500'); |
Per1 |
knockout |
|
|
|
|
|
|
|
| H |
circadian mutant |
Sleep |
mice |
Reference
11389837'); |
Per1, Per2 |
knockout |
|
|
|
|
|
|
|
| H |
circadian mutant |
Sleep |
mice |
Reference
11395012'); |
Per1, Per2, Per3 |
knockout |
|
|
|
|
|
|
|
| H |
circadian mutant; hypertension |
Sleep |
mice |
Reference
11302556 |
eNOS |
knockout |
|
|
|
|
|
|
|
| H |
circadian period, long |
Sleep |
mice |
Reference
8821757'); |
Whl (Wheels) |
other (mutant strain) |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
hamster |
Reference
9711506'); |
tau (Clock mutation) |
other (mutant strain) |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
8847666 |
c-fos |
other (null mutant) |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
9160755 |
Clock |
other (mutant strain) |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
10364217 |
CRE-B-galactosidase reporter |
transgenic |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
10581037 |
Crx(photoreceptor-specific transcription factor) |
knockout |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
10217146 |
Cry1 (cryptochrome receptor) |
transgenic |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
9987022 |
GR-impaired (GR-i) (glucocorticoid receptor impaired) |
transgenic |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
9822380'); |
mCry2 (cryptochrome receptor) |
knockout |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
11163178'); |
MOP3/BMAL1 |
knockout |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
9185559'); |
Ncamtm1Cwr mutation (neural cell adhesion molecule) |
other (mutant strain) |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
10036989'); |
nNOS-/- |
knockout |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
11441147'); |
NPAS2 |
conditional expression transgenic |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
10938103'); |
Per3 |
knockout |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
9619497'); |
rd/rd (retinal degenerate) |
transgenic |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
10098483'); |
rds (retinal degeneration slow) |
transgenic |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
10077319'); |
rdta (rod photoreceptor ablated) |
transgenic |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
10205061'); |
rdta/cl (rod and cone photoreceptor ablated) |
transgenic |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
9670004'); |
RORbeta-/- (orphan nuclear receptor) |
knockout |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
mice |
Reference
11027354'); |
VPAC(2) receptor |
transgenic |
|
|
|
|
|
|
|
| H |
circadian rhythm |
Sleep |
rat |
Reference
10784453'); |
Per1 |
transgenic |
|
|
|
|
|
|
|
| H |
circadian rhythm; hypertension |
Sleep |
rat |
Reference
11379663'); |
mREN2 |
transgenic |
|
|
|
|
|
|
|
| H |
circadian rhythm; hypertension |
Sleep |
rat |
Reference
10373099'); |
TGR(mREN2)27 (TGR) |
transgenic |
|
|
|
|
|
|
|
| H |
circadian sleep phase disorder |
Sleep |
mice |
Reference
12244319'); |
Rab3a |
"loss of function" knockout |
|
|
|
|
|
|
|
| LM |
Cirrhosis of the liver |
|
baboons |
Reference 1237225 |
|
|
|
|
|
|
|
|
|
| LM |
Cirrhosis of the liver |
|
rats |
Reference 1237225 |
|
|
|
|
|
|
|
|
|
| A |
Citrullinemia |
|
cattle |
18th Fascicle, AFIP, 1991 |
|
|
|
|
|
|
|
|
| H |
coagulation |
DBDR |
mice |
Reference
11145969 |
beta 2-glycoprotein |
knockout |
|
|
|
|
|
|
|
| H |
coagulation |
Blood |
mice |
Reference
7649481 |
fibrinogen A alpha |
knockout |
|
|
|
|
|
|
|
| H |
coagulation |
Blood |
mice |
Reference
9636195'); |
prothrombin |
knockout |
|
|
|
|
|
|
|
| H |
coagulation |
Blood |
mice |
Reference
8578517'); |
thrombomodulin |
knockout |
|
|
|
|
|
|
|
| H |
coagulation |
Blood |
mice |
Reference
9442117'); |
thrombospondin 2 |
knockout |
|
|
|
|
|
|
|
| H |
coagulation and inflammation |
Blood |
mice |
Reference
7720072 |
gelsolin |
knockout |
|
|
|
|
|
|
|
| H |
coagulation factor V deficiency |
Blood |
mice |
Reference
10669158 |
factor V minigene |
transgenic |
|
|
|
|
|
|
|
| M |
coat color |
|
mice |
DctSlt-lt |
B6.C3-DctSlt-lt/Hsd |
Spontaneous Mutant |
MMRRC:0150-H/M |
MMRRC Catalog |
Cryopreserved |
|
|
|
|
| MM |
coat color |
|
mice |
DctSlt-lt |
DctSlt-lt |
Spontaneous Mutant |
MMRRC:0150-H/M |
MMRRC Catalog |
B6.C3-DctSlt-lt/Hsd |
Cryopreserved |
|
|
|
| M |
coat color modifier genes |
|
mice |
am |
JULm.Cg-am/Hsd |
Targeted Mutation / Radiation Induced |
MMRRC:0155-H/M |
MMRRC
Catalog |
Cryopreserved |
|
|
|
|
| MM |
coat color modifier genes |
|
mice |
am |
am |
Targeted Mutation / Radiation Induced |
MMRRC:0155-H/M |
MMRRC
Catalog |
JULm.Cg-am/Hsd |
Cryopreserved |
|
|
|
| M |
coat color, modifier genes |
|
mice |
am |
JULm.Cg-am/Hsd |
Targeted Mutation / Radiation Induced |
MMRRC:0155-H/M |
MMRRC Catalog |
Cryopreserved |
|
|
|
|
| MM |
coat color, modifier genes |
|
mice |
am |
am |
Targeted Mutation / Radiation Induced |
MMRRC:0155-H/M |
MMRRC Catalog |
JULm.Cg-am/Hsd |
Cryopreserved |
|
|
|
| H |
cold agglutinin disease |
Blood |
mice |
Reference
9332312'); |
immunoglobulin M |
other |
|
|
|
|
|
|
|
| H |
colitis |
Blood |
mice |
Reference
9759840'); |
interleukin-10 (IL-10) |
knockout |
|
|
|
|
|
|
|
| LM |
colitis |
|
monkey, tamarins |
Reference 2493193 |
|
|
|
|
|
|
|
|
|
| D |
Colitis and Colon cancer |
|
Monkey, Tamarins |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| LM |
colitis, spontaneous |
|
cotton-top tamarin |
Reference 8536845 |
|
|
|
|
|
|
|
|
|
| LM |
colitis, ulcerative |
|
monkeys |
Reference 11383596 |
|
|
|
|
|
|
|
|
|
| H |
collagen I expression in lung |
Lung |
mice |
Reference
9584177 |
Col1A1 intron I |
knockout |
|
|
|
|
|
|
|
| LM |
colon cancer |
|
cotton-top tamarin |
Reference 8536845 |
|
|
|
|
|
|
|
|
|
| LM |
colon cancer |
|
monkey, tamarins |
Reference 2493193 |
|
|
|
|
|
|
|
|
|
| A |
Colonic Adenocarcinoma |
|
tamarins |
13th Fascicle, AFIP, 1984 |
|
|
|
|
|
|
|
|
| A |
Combined
Immunodeficiency Swiss-type Agammaglobulinemia |
|
horses |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| H |
complement regulation in transplantation |
Blood |
mice |
Reference
9869079 |
CD46 |
transgenic |
|
|
|
|
|
|
|
| H |
conduction defects in heart ventricular dysfunction |
Heart |
mice |
Reference
11535579 |
connexin43 (Cx43) |
heterogeneous expression |
|
|
|
|
|
|
|
| H |
conduction defects;heart failure |
Heart |
mice |
Reference
11457872 |
DNA nonbinding homeoprotein Nkx2.5 |
cardiac-specific mutation |
|
|
|
|
|
|
|
| LM |
Cone-rod dystrophy |
|
baboons |
Reference 822562 |
|
|
|
|
|
|
|
|
|
| A |
Congenital Athymia |
|
mice Lower Motor
Neuron Disease |
7th Fascicle, AFIP, 1978 |
|
|
|
|
|
|
|
|
| H |
congenital dyserythropoietic anemia type II |
Blood |
mice |
Reference
9230311 |
alpha-mannosidase-II |
knockout |
|
|
|
|
|
|
|
| A |
Congenital Goitre |
|
sheep |
16th Fascicle, AFIP, 1987 |
|
|
|
|
|
|
|
|
| H |
congenital heart disease; spina bifida |
Heart |
mice |
Reference
10226008'); |
Pax3 |
transgenic rescue, partial |
|
|
|
|
|
|
|
| A |
Congenital Hydrocephalus |
|
cattle |
8th Fascicle, AFIP, 1979 |
|
|
|
|
|
|
|
|
| A |
Congenital Hydrocephalus |
|
monkeys |
8th Fascicle, AFIP, 1979 |
|
|
|
|
|
|
|
|
| A |
Congenital Hydrocephalus |
|
rats |
13th Fascicle, AFIP, 1984 |
|
|
|
|
|
|
|
|
| A |
Congenital
Hyperbilirubinemia Gilbert's Syndrome |
|
sheep |
1st Fascicle, AFIP, 1972: |
|
|
|
|
|
|
|
|
| A |
Congenital
Hyperbilirubinemia, Crigler-Najjar Syndrome |
|
rats |
2nd Fascicle, AFIP, 1973: |
|
|
|
|
|
|
|
|
| A |
Congenital
Hyperbilirubinemia, Dubin-Johnson Syndrome |
|
Corriedale sheep |
1st Fascicle, AFIP, 1972: |
|
|
|
|
|
|
|
|
| A |
Congenital
Malformations of the Brain |
|
ferrets |
4th Fascicle, AFIP, 1975 |
|
|
|
|
|
|
|
|
| A |
Congenital Neonatal
Pneumonia |
|
monkeys |
13th Fascicle, AFIP, 1984 |
|
|
|
|
|
|
|
|
| A |
Congenital
Polycstic Kidney Disease |
|
mice |
13th Fascicle, AFIP, 1984 |
|
|
|
|
|
|
|
|
| A |
Congenital Porphyria |
|
fox squirrels |
7th Fascicle, AFIP, 1978 |
|
|
|
|
|
|
|
|
| H |
congestive heart failure;enhanced contractility |
Heart |
mice |
Reference
10571538'); |
potassium channel subunit K(v)4.2 |
transgenic |
|
|
|
|
|
|
|
| H |
conotruncal heart malformations, gap junctional communication
inhibition |
Heart |
mice |
Reference
9851855 |
alpha 1 connexin |
transgenic |
|
|
|
|
|
|
|
| H |
contractility of arterial smooth muscle |
Heart |
mice |
Reference
11159833'); |
insulin-like growth factor I (IGF-I) |
overexpression in smooth muscle |
|
|
|
|
|
|
|
| RR |
control strain for line RRRC:0043 |
|
rat |
Control |
HLA B7 |
|
LEW- Tg(HLA-B*0702,B2M)120-4Trg |
CM: Rat Resource Center |
RRRC:0042 |
Transgenic |
Live Colony |
|
|
| H |
coronary arterial thrombosis |
Heart |
mice |
Reference
12135951'); |
PAI-1 (plasminogen activator inhibitor) |
transgenic |
|
|
|
|
|
|
|
| H |
coronary vasculature, development and function of |
Heart |
mice |
Reference
10666423'); |
vascular endothelial growth factor (VEGF)-B |
knockout |
|
|
|
|
|
|
|
| LM |
Coxiella burnettii infection |
|
monkeys, cynomolgus macaques |
Reference 10638499 |
|
|
|
|
|
|
|
|
|
| H |
coxsackievirus B3-induced autoimmune myocarditis |
Heart |
mice |
Reference
10364312 |
gamma delta+ T cells |
transgenic |
|
|
|
|
|
|
|
| A |
Cretinism |
|
rats |
7th Fascicle, AFIP, 1978 |
|
|
|
|
|
|
|
|
| D |
Creutzfeldt-Jacob disease |
|
Monkey, Squirrel Monkeys |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| LM |
Creutzfeldt-Jakob Disease |
|
monkey |
Reference 4994933 |
|
|
|
|
|
|
|
|
|
| LM |
Creutzfeldt-Jakob Disease |
|
monkey, marmoset |
Reference 417327 |
|
|
|
|
|
|
|
|
|
| LM |
Crohn Disease |
|
monkeys |
Reference 11383596 |
|
|
|
|
|
|
|
|
|
| A |
Cryptococcal Meningitis |
|
rabbits |
14th Fascicle, AFIP, 1985 |
|
|
|
|
|
|
|
|
| LM |
cryptosporidiosis, diseminated -SIV induced |
|
monkey, macaca mulatta |
Reference 2823446 |
|
|
|
|
|
|
|
|
|
| A |
Cushing's
Syndrome, Hypercortisolism |
|
dogs |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| H |
cutaneous leishmaniasis |
Blood |
mice |
Reference
9815271'); |
interleukin-4 (IL-4) |
knockout |
|
|
|
|
|
|
|
| A |
Cyclic Neutropenia |
|
dog |
3rd Fascicle, AFIP, 1974: |
|
|
|
|
|
|
|
|
| H |
cyclosporine-induced hypertension |
Heart |
mice |
Reference
10920204'); |
synapsin I and II |
knockout |
|
|
|
|
|
|
|
| H |
cystic fibrosis |
Lung |
mice |
Reference
11978765 |
CFTR |
bi-transgenic |
|
|
|
|
|
|
|
| H |
cystic fibrosis |
Lung |
mice |
Reference
9215687 |
CFTR |
other (rescue) |
|
|
|
|
|
|
|
| H |
cystic fibrosis |
Lung |
mice |
Reference
7533607 |
CFTR |
knockout |
|
|
|
|
|
|
|
| H |
cystic fibrosis |
Lung |
mice |
Reference
10340937 |
CFTR |
other |
|
|
|
|
|
|
|
| H |
cystic fibrosis |
Lung |
mice |
Reference
8605891 |
CFTR G551D mutant |
other |
|
|
|
|
|
|
|
| H |
cystic fibrosis |
Lung |
mice |
Reference
9399953 |
CFTR mutant |
knockout |
|
|
|
|
|
|
|
| H |
cystic fibrosis |
Lung |
mice |
Reference
7540910 |
CFTR-M1 HGU mutant |
other |
|
|
|
|
|
|
|
| A |
Cystinuria |
|
rats |
17th Fascicle, AFIP, 1989 |
|
|
|
|
|
|
|
|
| LM |
Cytomegalovirus |
|
monkey, macaca |
Reference 6098169 |
|
|
|
|
|
|
|
|
|
| LM |
D retrovirus |
|
monkey, macaca mulatta |
Reference 6200929 |
|
|
|
|
|
|
|
|
|
| A |
Damage to DNA |
|
fish |
8th Fascicle, AFIP, 1979 |
|
|
|
|
|
|
|
|
| A |
Defective
Skeletal Muscle Glucose and/or Glycogen Metabolism |
|
rats |
10th Fascicle, AFIP, 1981 |
|
|
|
|
|
|
|
|
| LM |
Deltaretrovirus |
|
monkey, macaca fascicularis |
Reference 2903617 |
|
|
|
|
|
|
|
|
|
| LM |
dengue infections |
|
monkey, macaca |
Reference 4198027 |
|
|
|
|
|
|
|
|
|
| LM |
dengue infections |
|
monkey, macaca |
Reference 4198025 |
|
|
|
|
|
|
|
|
|
| LM |
dengue infections |
|
monkey, macaca |
Reference 4198024 |
|
|
|
|
|
|
|
|
|
| LM |
dental |
|
monkeys, cynomolgus macaques |
Reference 7062714 |
|
|
|
|
|
|
|
|
|
| A |
Dental Calculus |
|
dogs |
14th Fascicle, AFIP, 1985 |
|
|
|
|
|
|
|
|
| LM |
dental caries |
|
monkey, macaca mulatta |
Reference 808202 |
|
|
|
|
|
|
|
|
|
| LM |
dental caries |
|
monkey, macaca mulatta |
Reference 808201 |
|
|
|
|
|
|
|
|
|
| LM |
dental caries |
|
monkeys, cynomolgus macaques |
Reference 7062714 |
|
|
|
|
|
|
|
|
|
| LM |
dental trauma |
|
monkey, |
Reference 2894300 |
|
|
|
|
|
|
|
|
|
| H |
depressed cardiac contractility; cardiac hypertrophy |
Heart |
mice |
Reference
10809743'); |
phospholamban (PLN) |
transgenic overexpression |
|
|
|
|
|
|
|
| LM |
depression |
|
baboons |
Reference 413003 |
|
|
|
|
|
|
|
|
|
| H |
derivation of endothelial progenitor cells |
Blood |
mice |
Reference
10436164 |
Flk-1 or Tie-2 |
transgenic |
|
|
|
|
|
|
|
| A |
Dermatomyositis |
|
dogs |
15th Fascicle, AFIP, 1986 |
|
|
|
|
|
|
|
|
| H |
desmin-related cardiomyopathy |
Heart |
mice |
Reference
11352891 |
desmin |
transgenic |
|
|
|
|
|
|
|
| H |
development |
Lung |
mice |
Reference
10417821'); |
T1alpha promoter |
transgenic |
|
|
|
|
|
|
|
| H |
development (not required for normal cardiovascular regulation
and neuromuscular development) |
Heart |
mice |
Reference
10532808 |
alpha-calcitonin gene-related peptide (alphaCGRP) |
knockout |
|
|
|
|
|
|
|
| M |
Development / Neurobiology |
|
mice |
IGF1 (human) |
B6.Cg-Tg(Mt1/IGF-1)52Unc/Tac |
Transgenic |
MMRRC:0004-Tac/Alb |
MMRRC Catalog |
Live Colony, Non-Profit Only** |
|
|
|
|
| MM |
Development / Neurobiology |
|
mice |
IGF1 (human) |
IGF1 (human) |
Transgenic |
MMRRC:0004-Tac/Alb |
MMRRC Catalog |
B6.Cg-Tg(Mt1/IGF-1)52Unc/Tac |
Live Colony, Non-Profit
Only** |
|
|
| H |
development of cardiovascular and nervous systems, and limbs |
Heart |
mice |
Reference
8575331'); |
neuropilin |
overexpression in embryonic stem cell clones |
|
|
|
|
|
|
|
| H |
development of heart and kidney |
Heart |
rat |
Reference
10494802 |
endothelin-2(ET-2) |
transgenic |
|
|
|
|
|
|
|
| H |
development of heart, kidney, palate, and skeleton |
Heart |
mice |
Reference
8541217 |
alpha-myosin heavy chain (MHC)-Hoxb-7 |
transgenic |
|
|
|
|
|
|
|
| H |
development of humoral immune responses |
Blood |
mice |
Reference
9815267'); |
interleukin-6 (IL-6) |
knockout |
|
|
|
|
|
|
|
| H |
development of specialized functions in hematopoietic cells |
Blood |
mice |
Reference
10485650 |
G-CSF receptor |
knockout |
|
|
|
|
|
|
|
| H |
development, thrombosis |
Heart |
mice |
Reference
8632823'); |
thrombin receptor |
knockout |
|
|
|
|
|
|
|
| D |
Developmental biology |
|
Baboons |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| H |
developmental defects in heart and neural tube |
Heart |
mice |
Reference
9118799 |
connexin 43, targeted to dorsal neural tube and neural crest by cytomegaloviral promoter (CMV43) |
transgenic |
|
|
|
|
|
|
|
| D |
Diabetes |
|
Baboons |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| H |
diabetes |
Heart |
mice |
Reference
8990188 |
beta cell-specific T cell receptor x NOD.scid |
transgenic x NOD.scid background genes |
|
|
|
|
|
|
|
| H |
diabetes |
Heart |
mice |
Reference
9707599 |
glutamic acid decarboxylase (GAD)65 |
transgenic |
|
|
|
|
|
|
|
| H |
diabetes |
Heart |
mice |
Reference
9727063'); |
HLA-DQ8 |
transgenic |
|
|
|
|
|
|
|
| H |
diabetes |
Heart |
mice |
Reference
8738958'); |
interleukin-10 (IL-10) |
transgenic |
|
|
|
|
|
|
|
| H |
diabetes |
Heart |
mice |
Reference
9449718'); |
T cell receptor: BDC2.5 TCR with C57B1/6 background genes and two H-2(g7) alleles |
transgenic and other |
|
|
|
|
|
|
|
| H |
diabetes |
Heart |
mice |
Reference
8920883'); |
TNF alpha, tumor necrosis factor alpha in nonobese diabetic mice |
transgenic |
|
|
|
|
|
|
|
| D |
Diabetes |
|
Monkey, African Green Monkey |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| LM |
Diabetes II |
|
callitrichids |
Reference 12145399 |
|
|
|
|
|
|
|
|
|
| LM |
Diabetes II |
|
monkey |
Reference 128998 |
|
|
|
|
|
|
|
|
|
| LM |
Diabetes II |
|
monkey, macaca mulatta |
Reference 101670 |
|
|
|
|
|
|
|
|
|
| LM |
Diabetes II |
|
monkey, rheuses macaque |
Reference 2725553 |
|
|
|
|
|
|
|
|
|
| LM |
Diabetes II |
|
monkeys, callitrichids |
Reference 12145399 |
|
|
|
|
|
|
|
|
|
| A |
Diabetes Mellitus |
|
cats |
16th Fascicle, AFIP, 1987 |
|
|
|
|
|
|
|
|
| A |
Diabetes Mellitus |
|
dogs |
11th Fascicle, AFIP, 1982 |
|
|
|
|
|
|
|
|
| A |
Diabetes Mellitus |
|
fish |
6th Fascicle, AFIP, 1977 |
|
|
|
|
|
|
|
|
| A |
Diabetes Mellitus |
|
mice |
16th Fascicle, AFIP, 1987 |
|
|
|
|
|
|
|
|
| A |
Diabetes Mellitus |
|
mice Hirschsprung=s
Disease |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| A |
Diabetes Mellitus |
|
monkeys |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| A |
Diabetes Mellitus |
|
Mystromys |
8th Fascicle, AFIP, 1979 |
|
|
|
|
|
|
|
|
| A |
Diabetes Mellitus |
|
rabbits |
12th Fascicle, AFIP, 1983 |
|
|
|
|
|
|
|
|
| A |
Diabetes Mellitus |
|
rats |
10th Fascicle, AFIP, 1981 |
|
|
|
|
|
|
|
|
| H |
diabetes, target organ damage |
Heart |
mice |
Reference
7758869 |
aldose reductase |
transgenic |
|
|
|
|
|
|
|
| H |
diastolic heart function |
Heart |
mice |
Reference
8530495 |
beta-tropomyosin, striated muscle-specific, expressed in heart |
transgenic |
|
|
|
|
|
|
|
| LM |
DIC Disseminated Intravascular coagulation |
|
monkey, macaca mulatta |
Reference 98603 |
|
|
|
|
|
|
|
|
|
| A |
Diet-Induced
Thromboembolism and Myocardial Infarction |
|
rats |
9th Fascicle, AFIP, 1980 |
|
|
|
|
|
|
|
|
| H |
differentiation; growth of coronary system |
Heart |
mice |
Reference
10926871 |
fibroblast growth factor (FGF)-1 |
transgenic myocardial overexpression |
|
|
|
|
|
|
|
| H |
dilated cardiomyopathy |
Heart |
mice |
Reference
9769337 |
Coxsackievirus mutant (CVB3DeltaVP0) |
transgenic |
|
|
|
|
|
|
|
| H |
dilated cardiomyopathy |
Heart |
mice |
Reference
11984589 |
ErbB2 |
targeted deletion |
|
|
|
|
|
|
|
| H |
dilated cardiomyopathy |
Heart |
mice |
Reference
11717156'); |
PKA catalytic subunit |
transgenic expression in heart |
|
|
|
|
|
|
|
| H |
dilated cardiomyopathy |
Heart |
mice |
Reference
10993798'); |
protein phosphatase 2A |
transgenic |
|
|
|
|
|
|
|
| H |
dilated cardiomyopathy |
Heart |
mice |
Reference
11950896'); |
rae28 |
targeted or ubiquitous expression |
|
|
|
|
|
|
|
| H |
dilated cardiomyopathy |
Heart |
mice |
Reference
10675365'); |
retinoid X receptor alpha (RXR alpha) x RXR alpha-null |
transgenic cardiac overexpression |
|
|
|
|
|
|
|
| H |
dilated cardiomyopathy of Kearns-Sayre syndrome |
Heart |
mice |
Reference
9916807'); |
mitochondrial transcription factor A (Tfam, previously mtTFA) |
conditional mutation |
|
|
|
|
|
|
|
| H |
dilated cardiomyopathy, congestive heart failure |
Heart |
mice |
Reference
9329959'); |
retinoic acid receptor (RAR) |
transgenic cardiac overexpression |
|
|
|
|
|
|
|
| H |
dilated cardiomyopathy; pulmonary hypertension |
Heart |
mice |
Reference
12177436 |
Cav-1 |
knockout |
|
|
|
|
|
|
|
| A |
Disseminated
Intravascular Coagulation |
|
rats |
17th Fascicle, AFIP, 1989 |
|
|
|
|
|
|
|
|
| LM |
distemper virus, canine |
|
monkey, squirrel |
Reference 2338709 |
|
|
|
|
|
|
|
|
|
| H |
diuresis, hypotension, skeletal deformation |
Heart |
mice |
Reference
10377427'); |
natriuretic peptide receptor 3 (Npr3) |
knockout |
|
|
|
|
|
|
|
| H |
DNA damage |
Heart |
mice |
Reference
11033419 |
catalase |
overexpression in peroxisomes or nucleus |
|
|
|
|
|
|
|
| H |
dry eye; cutaneous xanthomatosis; atherosclerosis |
Heart |
mice |
Reference |
acyl-CoA:cholesterol acyltransferase (ACAT) |
knockout |
|
|
|
|
|
|
|
| LM |
dry eye; cutaneous xanthomatosis; atherosclerosis |
|
mice |
Reference |
|
|
|
|
|
|
|
|
|
| A |
Duodenal Ulcer Disease |
|
rats |
8th Fascicle, AFIP, 1979 |
|
|
|
|
|
|
|
|
| A |
Dysbaric Osteonecrosis |
|
mice |
10th Fascicle, AFIP, 1981 |
|
|
|
|
|
|
|
|
| LM |
Ebola |
|
monkey, macaca mulatta |
Reference 6138602 |
|
|
|
|
|
|
|
|
|
| LM |
EBV, Epstein-Barr virus |
|
monkeys, cottontop tamarins |
Reference 7943186 |
|
|
|
|
|
|
|
|
|
| H |
ectopic channel expression in ventricle |
Heart |
mice |
Reference
11668056'); |
K channel alpha subunit, Kv1.5 |
transgenic expression in myocardium |
|
|
|
|
|
|
|
| A |
Ectopic
Ossification of Healing Tendon |
|
rat |
19th Fascicle, AFIP, 1993 |
|
|
|
|
|
|
|
|
| A |
Ehlers-Danlos Syndrome |
|
dogs and mink |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| H |
Ehlers-Danlos syndrome, type IV; normal collagen I
fibrillogenesis |
Heart |
mice |
Reference
9050868 |
collagen 3A1 |
recombinant DNA |
|
|
|
|
|
|
|
| LM |
Elephantiasis |
|
monkey, silver leaf |
Reference 3312807 |
|
|
|
|
|
|
|
|
|
| H |
embryogenesis, heart development |
Heart |
mice |
Reference
10944220'); |
serotonin 2B receptor |
mutation |
|
|
|
|
|
|
|
| H |
embryonic angiogenesis |
Heart |
mice |
Reference
11880349 |
ephrinB2 |
vascular-specific deletion |
|
|
|
|
|
|
|
| H |
embryonic craniofacial and cardiac abnormalities |
Heart |
mice |
Reference
9449665 |
endothelin converting enzyme (ECE-1) |
knockout |
|
|
|
|
|
|
|
| M |
Embryonic development
of:/ melanocytes / hematopoietic stem cells/ germ cells |
mice |
KitW-2J |
JULm.B6-KitW-2J/Hsd |
Spontaneous Mutation |
MMRRC:0177-H/M |
MMRRC Catalog |
Cryopreserved |
|
|
|
|
| MM |
Embryonic development
of:/ melanocytes / hematopoietic stem cells/ germ cells |
mice |
KitW-2J |
KitW-2J |
Spontaneous Mutation |
MMRRC:0177-H/M |
MMRRC Catalog |
JULm.B6-KitW-2J/Hsd |
Cryopreserved |
|
|
|
| H |
embryonic heart and skeletal muscle development |
Heart |
mice |
Reference
8626009 |
desmin |
transgenic |
|
|
|
|
|
|
|
| H |
embryonic left-right patterning, cardiac anomalies |
Heart |
mice |
Reference
10700179 |
growth/differentiation factor (Gdf)-1 |
mutation |
|
|
|
|
|
|
|
| H |
emphysema |
Lung |
mice |
Reference
10353442 |
alpha1-antitrypsin (alpha1AT) |
transgenic |
|
|
|
|
|
|
|
| H |
emphysema |
Lung |
mice |
Reference
10615062'); |
klotho |
knockout |
|
|
|
|
|
|
|
| H |
emphysema |
Lung |
mice |
Reference
9302297'); |
macrophage metalloelastase (MME) |
knockout |
|
|
|
|
|
|
|
| H |
emphysema; airway remodeling |
Lung |
mice |
Reference
9366564'); |
interleukin-11 (IL-11), inducible |
transgenic |
|
|
|
|
|
|
|
| H |
emphysema; fibrotic lung disease; inflammation |
Lung |
mice |
Reference
10362801'); |
PDGF-B |
transgenic |
|
|
|
|
|
|
|
| LM |
Encephalitis |
|
monkey, squirrel |
Reference 2338709 |
|
|
|
|
|
|
|
|
|
| LM |
encephalomyelopathy, demyelinating |
|
monkey |
Reference 5440319 |
|
|
|
|
|
|
|
|
|
| LM |
encephalopathies |
|
monkey |
Reference 4994933 |
|
|
|
|
|
|
|
|
|
| LM |
encephalopathy, spontaneous spongiform |
|
monkey, macaca mulatta |
Reference 8843820 |
|
|
|
|
|
|
|
|
|
| A |
Endocardial Fibroelastosis
|
|
cats |
11th Fascicle, AFIP, 1982 |
|
|
|
|
|
|
|
|
| A |
Endometrial Adenocarcinoma
|
|
rabbit |
2nd Fascicle, AFIP, 1973: |
|
|
|
|
|
|
|
|
| LM |
Endometriosis |
|
baboons |
Reference 12733601 |
|
|
|
|
|
|
|
|
|
| LM |
Endometriosis |
|
baboons |
Reference 1487181 |
|
|
|
|
|
|
|
|
|
| LM |
Endometriosis |
|
monkey, macaca mulatta |
Reference 3097054 |
|
|
|
|
|
|
|
|
|
| A |
Endometriosis |
|
monkeys |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| H |
endothelial activation in acute hepatitis |
Blood |
mice |
Reference
11564813'); |
tumor necrosis factor |
transgenic |
|
|
|
|
|
|
|
| H |
endothelial cells |
Blood |
mice |
Reference
9281588'); |
von Willebrand factor |
transgenic |
|
|
|
|
|
|
|
| H |
endothelial cells |
Heart |
mice |
Reference
9281588'); |
von Willebrand factor |
transgenic |
|
|
|
|
|
|
|
| H |
endothelial cells |
Blood |
mice |
Reference
7753844'); |
von Willebrand factor-beta galactosidase |
transgenic |
|
|
|
|
|
|
|
| H |
endothelium, transcriptional specificity to |
Heart |
mice |
Reference
9864160'); |
vascular endothelial-cadherin: promoter chimeric construct containing (-2486,+24) |
transgenic |
|
|
|
|
|
|
|
| H |
endotoxemia |
Heart |
mice |
Reference
10775120 |
heat shock protein HSP70 |
transgenic cardiac-specific overexpression |
|
|
|
|
|
|
|
| H |
endotoxic shock |
Blood |
mice |
Reference
10811868 |
CC chemokine receptor 4 |
knockout |
|
|
|
|
|
|
|
| LM |
Enteeropathy, resembling sprue |
|
monkey |
Reference 4113959 |
|
|
|
|
|
|
|
|
|
| A |
Enteropathogenic
Eschericia Coli Infection |
|
apes |
6th Fascicle, AFIP, 1977 |
|
|
|
|
|
|
|
|
| A |
Eosinophilic
Meningoencephalitis |
|
mice |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| H |
epicardial development |
Heart |
mice |
Reference
12021259 |
[alpha] 4 [beta] 1 integrin, alpha4 subunit |
knock-in |
|
|
|
|
|
|
|
| H |
epidermolysis bullosa simplex (EBS)-MD; muscular dystrophy;
cardiomyopathy |
Heart |
mice |
Reference
9389647'); |
plectin |
knockout |
|
|
|
|
|
|
|
| LM |
Epilepsy |
|
monkey, squirrel |
Reference 2338709 |
|
|
|
|
|
|
|
|
|
| MM |
Epilepsy/ Ganglioside function |
|
mice |
Siat8a |
Siat8a |
Targeted Mutation / Knockout |
MMRRC:0037-H/M |
MMRRC Catalog |
B6;129S-Siat8atm1Rlp/Hsd |
Cryopreserved |
|
|
|
| LM |
Epstein-Barr |
|
monkey, Aotus trivirgatus |
Reference 190472 |
|
|
|
|
|
|
|
|
|
| LM |
Epstein-Barr |
|
monkey, marmoset |
Reference 205860 |
|
|
|
|
|
|
|
|
|
| LM |
Epstein-Barr |
|
monkeys, cottontop tamarins |
Reference 7943186 |
|
|
|
|
|
|
|
|
|
| LM |
Erythroblastosis |
|
monkey, macaca mulatta, fascicularis |
Reference 808623 |
|
|
|
|
|
|
|
|
|
| H |
erythrocyte maturation |
Blood |
mice |
Reference
10983976 |
E2F4 transcription factor |
knockout |
|
|
|
|
|
|
|
| H |
erythrocyte membrane biogenesis |
DBDR |
mice |
Reference
11313283 |
glycophorin A |
transgenic |
|
|
|
|
|
|
|
| H |
erythrocyte membrane structure |
Blood |
mice |
Reference
9490702 |
band 3 (AE1) |
knockout |
|
|
|
|
|
|
|
| H |
erythrocyte oxidative stress; anemia |
DBDR |
mice |
Reference
11264184'); |
p45NF-E2 |
knockout |
|
|
|
|
|
|
|
| H |
erythroid differentiation |
Blood |
mice |
Reference
9139715 |
GATA-1 |
knockout |
|
|
|
|
|
|
|
| H |
erythropoiesis |
Blood |
mice |
Reference
9376585 |
Bcl-2 |
transgenic |
|
|
|
|
|
|
|
| H |
erythropoiesis |
Blood |
mice |
Reference
9808048 |
erythropoietin receptor |
transgenic |
|
|
|
|
|
|
|
| H |
erythropoiesis |
Blood |
mice |
Reference
11940669 |
FOG-1 |
knock-in |
|
|
|
|
|
|
|
| H |
erythropoiesis |
DBDR |
mice |
Reference
11566888 |
GATA-1 transcription factor |
transgenic and knockout |
|
|
|
|
|
|
|
| A |
Esophageal Achalasia |
|
dogs and cats |
8th Fascicle, AFIP, 1979 |
|
|
|
|
|
|
|
|
| A |
Esophageal Carcinoma |
|
rats |
9th Fascicle, AFIP, 1980 |
|
|
|
|
|
|
|
|
| H |
ET-1 expression to hypoxia |
Lung |
mice |
Reference
9357861'); |
preproendothelin-1 promoter-luciferase |
transgenic |
|
|
|
|
|
|
|
| A |
Experimental
Allergic Encephalomyelitis (EAE): a Model of Multiple Sclerosis |
nonhuman primates |
20th Fascicle, AFIP, 1995 |
|
|
|
|
|
|
|
|
| A |
Experimental
Myelocytic Leukemia as a Model for Pulminary Leukostatis |
brown Norway rat |
19th Fascicle, AFIP, 1993 |
|
|
|
|
|
|
|
|
| H |
Fabry disease; renal failure; cardiac and cerebrovascular
disease |
Heart |
mice |
Reference
10339603 |
alpha-galactosidase A |
knockout |
|
|
|
|
|
|
|
| A |
Falciparum Malaria |
|
hampsters |
18th Fascicle, AFIP, 1991 |
|
|
|
|
|
|
|
|
| H |
familial hypercholesterolemia |
Heart |
mice |
Reference
9701246'); |
low density lipoprotein (LDL) receptor; cannot edit apoB mRNA |
knockout and other manipulations |
|
|
|
|
|
|
|
| A |
Familial
Hypercholesterolemia |
|
Watanabe Heritable Hyperlipidemic
rabbit |
19th Fascicle, AFIP, 1993 |
|
|
|
|
|
|
|
|
| H |
familial hypertrophic cardiomyopathy |
Heart |
mice |
Reference
10948063 |
essential myosin light chain |
transgenic |
|
|
|
|
|
|
|
| H |
familial hypertrophic cardiomyopathy |
Heart |
mice |
Reference
10532952'); |
myosin binding protein C (MyBP-C) |
transgenic |
|
|
|
|
|
|
|
| H |
familial hypertrophic cardiomyopathy |
Heart |
mice |
Reference
11055985'); |
troponin I, cardiac (cTnI) |
transgenic cardiac-specific expression |
|
|
|
|
|
|
|
| H |
familial hypertrophic cardiomyopathy |
Heart |
rat |
Reference
10946062 |
cardiac troponin T |
transgenic |
|
|
|
|
|
|
|
| H |
familial hypertrophic cardiomyopathy (HCM) |
Heart |
mice |
Reference
8898372'); |
myosin heavy chain |
transgenic |
|
|
|
|
|
|
|
| H |
familial hypertrophic myopathy |
Heart |
mice |
Reference
10400910 |
alpha-tropomyosin |
transgenic underexpression |
|
|
|
|
|
|
|
| H |
familial LCAT deficiency, atherosclerosis |
Heart |
mice |
Reference
11278414'); |
lecithin cholesterol acyltransferase (LCAT) |
knockout |
|
|
|
|
|
|
|
| H |
Fanconi anemia |
Blood |
mice |
Reference
12135664 |
FancA; FancC |
knockout |
|
|
|
|
|
|
|
| H |
Fanconi anemia |
Blood |
mice |
Reference
11719385 |
FancG |
knockout |
|
|
|
|
|
|
|
| H |
Fanconi anemia |
Blood |
mice |
Reference
11823446 |
FancG |
knockout |
|
|
|
|
|
|
|
| H |
Fanconi anemia |
Blood |
mice |
Reference
8704201 |
Fanconi anemia C |
knockout |
|
|
|
|
|
|
|
| H |
Fanconi anemia |
Blood |
mice |
Reference
9650445 |
Fanconi anemia complementation group C |
knockout |
|
|
|
|
|
|
|
| H |
Fanconi's anemia |
Blood |
mice |
Reference
10082135 |
Fanconi anemia C |
knockout |
|
|
|
|
|
|
|
| A |
Fatal Arenavirus Infection
|
|
guinea pigs. |
13th Fascicle, AFIP, 1984 |
|
|
|
|
|
|
|
|
| A |
Fatty Liver and Cirrhosis |
|
rats |
4th Fascicle, AFIP, 1975 |
|
|
|
|
|
|
|
|
| LM |
Fetal Alchohol Syndromw |
|
monkey, nemestrina |
Reference 6563986 |
|
|
|
|
|
|
|
|
|
| A |
Fetal Growth Retardation |
|
rats |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| A |
Fetal Pneumonia |
|
monkeys. |
9th Fascicle, AFIP, 1980 |
|
|
|
|
|
|
|
|
| H |
fibrinolysis |
Blood |
mice |
Reference
9892694'); |
plasminogen activator inhibitor-2 |
knockout |
|
|
|
|
|
|
|
| LM |
Filariasis |
|
monkey, macaca mulatta, fascicularis |
Reference 107818 |
|
|
|
|
|
|
|
|
|
| M |
Folliculogenesis/ female infertility/ |
|
mice |
Figla |
STOCK Figlatm1Dean/Unc |
Targeted Mutation / Knockout |
MMRRC:0030-UNC |
MMRRC Catalog |
Live Colony |
|
|
|
|
| MM |
Folliculogenesis/ female infertility/ |
|
mice |
Figla |
Figla |
Targeted Mutation / Knockout |
MMRRC:0030-UNC |
MMRRC Catalog |
STOCK Figlatm1Dean/Unc |
Live Colony |
|
|
|
| H |
Friedreich ataxia |
Heart |
mice |
Reference
11175786 |
frataxin |
conditional gene-targeting |
|
|
|
|
|
|
|
| A |
Fucosidosis |
|
dogs |
17th Fascicle, AFIP, 1989 |
|
|
|
|
|
|
|
|
| H |
galactosialidosis |
Blood |
mice |
Reference
7590240'); |
protective protein/cathepsin A |
knockout |
|
|
|
|
|
|
|
| A |
Gastric Ulcer Disease |
|
Mastromys |
10th Fascicle, AFIP, 1981 |
|
|
|
|
|
|
|
|
| LM |
Gastritis |
|
monkey, macaca mulatta |
Reference 2229353 |
|
|
|
|
|
|
|
|
|
| LM |
Gastritis |
|
monkey, macaca mulatta |
Reference 3172170 |
|
|
|
|
|
|
|
|
|
| LM |
Gastritis |
|
monkeys, rhesus |
Reference 7650173 |
|
|
|
|
|
|
|
|
|
| LM |
Gastritis, chronic Type B |
|
monkey, nemestrina |
Reference 3183019 |
|
|
|
|
|
|
|
|
|
| LM |
Gastritis, trichomonas - SIV |
|
monkey, macaca mulatta |
Reference 2834463 |
|
|
|
|
|
|
|
|
|
| A |
Gastrointestinal Polyps |
|
dogs |
15th Fascicle, AFIP, 1986 |
|
|
|
|
|
|
|
|
| A |
Gaucher's Disease |
|
dogs |
11th Fascicle, AFIP, 1982 |
|
|
|
|
|
|
|
|
| A |
Generalised
Glycogenosis Type II |
|
cattle |
12th Fascicle, AFIP, 1983 |
|
|
|
|
|
|
|
|
| D |
Genetics characterization |
|
Monkey, Squirrel Monkeys |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| D |
Genetics Studies |
|
Baboons |
DRM Wkshop |
|
|
|
|
|
|
|
|
|
| A |
Genital Herpes |
|
guinea pigs |
11th Fascicle, AFIP, 1982 |
|
|
|
|
|
|
|
|
| A |
Gestational Diabetes |
|
mice |
15th Fascicle, AFIP, 1986 |
|
|
|
|
|
|
|
|
| LM |
GET ARTICLE |
|
|
Reference 1527793 |
|
|
|
|
|
|
|
|
|
| A |
Giardiasis |
|
mice |
7th Fascicle, AFIP, 1978 |
|
|
|
|
|
|
|
|
| LM |
Gilbert Disease |
|
monkey, squirrel, Bolivian |
Reference 2213857 |
|
|
|
|
|
|
|
|
|
| LM |
Gilbert Syndrome |
|
monkey, squirrel |
Reference 3999115 |
|
|
|
|
|
|
|
|
|
| A |
Gilbert's Syndrome |
|
monkeys |
14th Fascicle, AFIP, 1985 |
|
|
|
|
|
|
|
|
| LM |
gingival hyperplasia |
|
monkey, macaca mulatta |
Reference 405470 |
|
|
|
|
|
|
|
|
|
| A |
Gingival Hyperplasia |
|
dogs |
18th Fascicle, AFIP, 1991 |
|
|
|
|
|
|
|
|
| LM |
gingivitis |
|
monkey, macaca mulatta |
Reference 405470 |
|
|
|
|
|
|
|
|
|
| LM |
Gingivitis |
|
monkey, squirrel |
Reference 3457397 |
|
|
|
|
|
|
|
|
|
| LM |
Gingivitis |
|
monkeys, cynomolgus macaques |
Reference 1625153 |
|
|
|
|
|
|
|
|
|
| H |
Glanzmann thrombasthenia |
Blood |
mice |
Reference
9916135'); |
integrin beta 3 |
knockout |
|
|
|
|
|
|
|
| H |
Glanzmann thrombasthenia |
Blood |
mice |
Reference
10942384'); |
platelet integrin alpha(IIb), beta(3) |
knockout |
|
|
|
|
|
|
|
| LM |
GLD, Globoid Cell Leukodystrophy |
|
monkey, rheuses |
Reference 9192853 |
|
|
|
|
|
|
|
|
|
| A |
Globoid Cell
Leukodystrophy |
|
dog |
1st Fascicle, AFIP, 1972: |
|
|
|
|
|
|
|
|
| A |
Globoid Cell
Leukodystrophy |
|
mice |
12th Fascicle, AFIP, 1983 |
|
|
|
|
|
|
|
|
| H |
glomerulosclerosis and liver alteration |
Heart |
mice |
Reference
7627093 |
growth hormone, bovine (bGH), specific expression in heart and striated muscle |
transgenic |
|
|
|
|
|
|
|
| LM |
Glucose intolerance |
|
monkey, macaca mulatta |
Reference 101670 |
|
|
|
|
|
|
|
|
|
| A |
Glutathione Deficiency |
|
sheep |
6th Fascicle, AFIP, 1977 |
|
|
|
|
|
|
|
|
| H |
glycogen storage disease type II |
Heart |
mice |
Reference
9668092 |
alpha-glucosidase (6(neo)/6(neo)) |
knockout |
|
|
|
|
|
|
|
| H |
glycogen storage disease type II (Pompe disease); cardiac
hypertrophy |
Heart |
mice |
Reference
9384603 |
alpha-glucosidase |
knockout |
|
|
|
|
|
|
|
| A |
Glycogen Storage
Disease type IV |
|
felines |
20th Fascicle, AFIP, 1995 |
|
|
|
|
|
|
|
|
| A |
Glycogenosis Type III |
|
dog. |
7th Fascicle, AFIP, 1978 |
|
|
|
|
|
|
|
|
| A |
GM1 Gangliosidosis |
|
cat |
4th Fascicle, AFIP, 1975 |
|
|
|
|
|
|
|
|
| A |
GM1 Gangliosidosis Type II
|
|
cattle |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| A |
GM2 gangliosidosis |
|
dog |
3rd Fascicle, AFIP, 1974: |
|
|
|
|
|
|
|
|
| A |
GM2 Gangliosidosis |
|
pigs |
6th Fascicle, AFIP, 1977 |
|
|
|
|
|
|
|
|
| A |
Gonorrhea |
|
cattle |
5th Fascicle, AFIP, 1976 |
|
|
|
|
|
|
|
|
| A |
Gonorrhea |
|
chimpanzee |
6th Fascicle, AFIP, 1977 |
|
|
|
|
|
|
|
|
| H |
graft-versus-host disease |
Blood |
mice |
Reference
8608208 |
granzyme A/diptheria toxin A |
transgenic |
|
|
|
|
|
|
|
| H |
graft-versus-host disease |
Blood |
mice |
Reference
9192790'); |
HSV thymidine kinase |
transgenic |
|
|
|
|
|
|
|
| H |
graft-versus-host disease |
Blood |
mice |
Reference
9670937'); |
interferon-gamma |
knockout |
|
|
|
|
|
|
|
| H |
graft-versus-host disease |
Blood |
mice |
Reference
9854048'); |
interferon-gamma |
knockout |
|
|
|
|
|
|
|
| H |
graft-versus-host disease |
Blood |
mice |
Reference
9678759'); |
interferon-gamma, TNF receptor I/II, and perforin |
knockout |
|
|
|
|
|
|
|
| A |
Granulomatous
Lesions of Helminth Origin |
|
mice |
6th Fascicle, AFIP, 1977 |
|
|
|
|
|
|
|
|
| H |
granulopoiesis |
Blood |
mice |
Reference
9376584 |
granulocyte colony-stimulating factor, and granulocyte-macrophage colony-stimulating factor |
knockout |
|
|
|
|
|
|
|
| H |
granulopoiesis |
Lung |
mice |
Reference
9376584 |
granulocyte colony-stimulating factor, and granulocyte-macrophage colony-stimulating factor |
knockout |
|
|
|
|
|
|
|
| A |
Gross Congenital Anomalies
|
|
several species |
1st Fascicle, AFIP, 1972: |
|
|
|
|
|
|
|
|
| A |
Gyrate
Atrophy of the Choroid and Retina |
|
cats. |
12th Fascicle, AFIP, 1983 |
|
|
|
|
|
|
|
|
| A |
Hageman Trait |
|
cats |
12th Fascicle, AFIP, 1983 |
|
|
|
|
|
|
|
|
| A |
Halothane-Assiciated
Hepatitis |
|
rats |
14th Fascicle, AFIP, 1985 |
|
|
|
|
|
|
|
|
| A |
Halothane-associated
Hepatitis |
|
guinea pig |
20th Fascicle, AFIP, 1995 |
|
|
|
|
|
|
|
|
| LM |
Haplorhini |
|
monkey |
Reference 2561344 |
|
|
|
|
|
|
|
|
|
| A |
Hashimoto's Disease |
|
dogs |
7th Fascicle, AFIP, 1978 |
|
|
|
|
|
|
|
|
| LM |
HAV, Hepatitis A |
|
monkeys, cynomolgus macaques |
Reference 3193448 |
|
|
|
|
|
|
|
|
|
| LM |
HAV, Hepatitis A |
|
monkeys, marmosets |
Reference 11930901 |
|
|
|
|
|
|
|
|
|
| LM |
HCV - neg finding |
|
monkey, cottontop tamarin |
Reference 9210038 |
|
|
|
|
|
|
|
|
|
| LM |
Heart |
|
cat |
Reference 6447412 |
|
|
|
|
|
|
|
|
|
| LM |
Heart |
|
dog |
Reference 6447412 |
|
|
|
|
|
|
|
|
|
| H |
heart cell-cycle regulation |
Heart |
mice |
Reference
11230113 |
cyclin-dependent kinase 2 (cdk2) |
cardiac-specific overexpression |
|
|
|
|
|
|
|
| H |
heart chamber development |
Heart |
chicken, mice |
Reference
10864469'); |
T-box (tbx5) |
targeted expression |
|
|
|
|
|
|
|
| H |
heart contractile dysfunction |
Heart |
mice |
Reference
11162127'); |
RGS4; Galpha q |
dual transgenic |
|
|
|
|
|
|
|
| H |
heart development |
Heart |
mice |
Reference
11440973 |
Cre recombinase |
heart-specific, inducible |
|
|
|
|
|
|
|
| H |
heart development |
Heart |
mice |
Reference
10651906'); |
receptor tyrosine kinase (mRor2) |
mutation |
|
|
|
|
|
|
|
| H |
heart development and cell proliferation |
Heart |
mice |
Reference
9590171'); |
transcriptional integrator p300 |
knockout |
|
|
|
|
|
|
|
| H |
heart development and function, ventricular septal defect |
Heart |
mice |
Reference
10807864'); |
Jumonji (jmj) |
mutation |
|
|
|
|
|
|
|
| M |
heart disease |
|
mice |
Pln |
STOCK Plntm1Egk Tg(Pln)11Egk/Hsd |
Transgenic & Knockout |
MMRRC:0052-H/M |
MMRRC Catalog |
Live Colony |
|
|
|
|
| M |
heart disease |
|
mice |
Pln |
STOCK Plntm1Egk Tg(Pln)22Egk/Hsd |
Transgenic & Knockout |
MMRRC:0053-H/M |
MMRRC Catalog |
Live Colony |
|
|
|
|
| M |
heart disease |
|
mice |
Pln |
FVB-Tg(Pln)416Egk/Tac |
Transgenic |
MMRRC:0061-Tac/Alb |
MMRRC Catalog |
Live Colony |
|
|
|
|
| MM |
heart disease |
|
mice |
Pln |
Pln |
Transgenic & Knockout |
MMRRC:0052-H/M |
MMRRC Catalog |
STOCK Plntm1Egk Tg(Pln)11Egk/Hsd |
Live Colony |
|
|
|
| MM |
heart disease |
|
mice |
Pln |
Pl
|