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  Locked-In Syndrome 
  
Reviewed  07-01-2001  

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Table of Contents (click to jump to sections)

What is Locked-In Syndrome?
Is there any treatment?
What is the prognosis?
What research is being done?

Organizations

What is Locked-In Syndrome?
Locked-in syndrome is a rare neurological disorder characterized by complete paralysis of voluntary muscles in all parts of the body (except for those that control eye movement). It may result from traumatic brain injury, vascular diseases, demyelinating diseases, or medication overdose. Individuals with locked-in syndrome are conscious and have cognitive function, but are unable to speak or move. The disorder leaves the patient completely mute and paralyzed. Communication may be possible with blinking eye movements.

Is there any treatment?
There is no cure for locked-in syndrome, nor is there a standard course of treatment. Functional neuromuscular stimulation may help activate some paralyzed muscles. Several devices to help communication are available. Other treatment is symptomatic and supportive.

What is the prognosis?
The prognosis for those with locked-in syndrome is poor. The majority of patients do not regain function.

What research is being done?
The NINDS supports research on neurological disorders such as stroke which may result in locked-in syndrome. The goals of this research are to find ways to prevent, treat, and cure these disorders.

Select this link to view a list of studies currently seeking patients.

 Organizations

National Rehabilitation Information Center (NARIC)
4200 Forbes Boulevard
Suite 202
Lanham, MD 20706-4829
naricinfo@heitechservices.com
http://www.naric.com
Tel: 301-562-2400 800-346-2742
Fax: 301-562-2401


NINDS health-related material is provided for information purposes only and does not necessarily represent endorsement by or an official position of the National Institute of Neurological Disorders and Stroke or any other Federal agency. Advice on the treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient's medical history.

All NINDS-prepared information is in the public domain and may be freely copied. Credit to the NINDS or the NIH is appreciated.


Provided by:
The National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, MD 20892




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