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Corticobasal Degeneration Reviewed 3-21-2003 Get Web page suited for printing Email this to a friend or colleague Studies with patients Table of Contents (click to jump to sections) What is Corticobasal Degeneration?Is there any treatment? What is the prognosis? What research is being done? Organizations Related NINDS Publications and Information What is Corticobasal Degeneration? Corticobasal degeneration is a progressive neurological disorder characterized by nerve cell loss and atrophy (shrinkage) of multiple areas of the brain including the cerebral cortex and the basal ganglia. Corticobasal degeneration progresses gradually. Initial symptoms, which typically begin at or around age 60, may first appear on one side of the body (unilateral), but eventually affect both sides as the disease progresses. Symptoms are similar to those found in Parkinson disease, such as poor coordination, akinesia (an absence of movements), rigidity (a resistance to imposed movement), disequilibrium (impaired balance); and limb dystonia (abnormal muscle postures). Other symptoms such as cognitive and visual-spatial impairments, apraxia (loss of the ability to make familiar, purposeful movements), hesitant and halting speech, myoclonus (muscular jerks), and dysphagia (difficulty swallowing) may also occur. An individual with corticobasal degeneration eventually becomes unable to walk. Is there any treatment? What is the prognosis? What research is being done? National Organization for Rare Disorders (NORD)
Worldwide Education & Awareness for Movement
Disorders (WE MOVE) Related NINDS Publications and Information
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