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Studies with patientsTable of Contents (click to jump to sections)
What is Arachnoiditis?
Is there any treatment?
What is the prognosis?
What research is being done?
Organizations
What is Arachnoiditis?
Arachnoiditis is an inflammatory response of the arachnoid, one of three coverings, or meninges, that envelop the brain and spinal cord. It may result from infection, including syphilis and tubercular meningitis; trauma (including that resulting from surgery, lumbar puncture, and spinal anesthesia); or a diagnostic procedure called a myelogram, which is performed in patients prior to spinal surgery. Symptoms include numbness, tingling, and a characteristic stinging and burning pain in the legs.Is there any treatment?
The goal of treatment should be to return the patient to a functional role in society. Conservative therapy such as pain management is generally recommended. In those patients whose arachnoiditis is progressive, surgery to remove adhesions is only minimally effective because scar tissue continues to develop. Also, surgery exposes the already irritated spinal cord to additional trauma.
What is the prognosis?
There is no cure for arachnoiditis. For the majority of patients, arachnoiditis is a disabling disease causing intractable pain and neurological deficits. As the disease progresses, some symptoms may increase and become permanent. Few people with this disorder are able to continue working. In some cases, progressive paraplegia may occur.
What research is being done?
Within the NINDS research programs, arachnoiditis is addressed primarily through studies associated with pain research. NINDS vigorously pursues a research program seeking new treatments for pain and nerve damage with the ultimate goal of reversing debilitating conditions such as arachnoiditis. NINDS has notified research investigators that it is seeking grant applications both in basic and clinical pain research. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and the National Institute of Dental Research (NIDR) may also be conducting research on pain.
Select this link to view a list of studies currently seeking patients.
OrganizationsAmerican Chronic Pain Association (ACPA)
P.O. Box 850
Rocklin, CA
95677-0850
ACPA@pacbell.net
http://www.theacpa.org
Tel: 916-632-0922
800-533-3231
Fax: 916-632-3208
National Chronic Pain Outreach Association
(NCPOA)
P.O. Box 274
Millboro, VA
24460
ncpoa@cfw.com
http://www.chronicpain.org
Tel: 540-862-9437
Fax: 540-862-9485
National Institute of Arthritis and
Musculoskeletal and Skin Diseases (NIAMS)
National Institutes of Health
Bldg. 31, Rm. 4C05
Bethesda, MD
20892-2350
NIAMSInfo@mail.nih.gov
http://www.nih.gov/niams
Tel: 301-496-8188
877-22-NIAMS (226-4267)
National Institute of Dental and Craniofacial
Research (NIDCR)
National Institutes of Health
Bldg. 45, Rm. 4AS19
Bethesda, MD
20892-6400
nidrinfo@od31.nidr.nih.gov
http://www.nidr.nih.gov
Tel: 301-496-4261
NINDS health-related material is provided for information purposes only and does not necessarily represent endorsement by or an official position of the National Institute of Neurological Disorders and Stroke or any other Federal agency. Advice on the treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient's medical history.
All NINDS-prepared information is in the public domain and may be freely copied. Credit to the NINDS or the NIH is appreciated.
Provided by:
The National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, MD 20892
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